Path dependence of three-phase or two-phase end points in fluid binary lipid mixtures.

Path dependence of three-phase or two-phase end points in fluid binary lipid mixtures.
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DOI:
10.1021/jp810326w
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发表时间:
2009-03-19
期刊:
The journal of physical chemistry. B
影响因子:
--
通讯作者:
Hovis JS
Hovis JS
中科院分区:
其他
文献类型:
--
作者:
Lamberson ER;Cambrea LR;Rochet JC;Hovis JS

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The phase behavior of anionic/zwitterionic mixtures can be controlled by tuning the charge state of the anionic lipid. In the case of dioleoylphosphatidic acid (DOPA)/dioleoylphosphatidylcholine (DOPC) mixtures, demixing occurs either when DOPA is protonated or when DOPA2−:Ca2+ complexes form. Herein it will be shown that the final endpoint, a three-phase or two-phase system, depends on the order in which the charge state is manipulated. The facile accessibility of different endpoints is a clear demonstration of the inherent flexibility of biological systems.
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