Semen Quality in Chinese College Students: Associations With Depression and Physical Activity in a Cross-Sectional Study
Semen Quality in Chinese College Students: Associations With Depression and Physical Activity in a Cross-Sectional Study
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中国大学生精液质量：横断面研究中抑郁症和体力活动的关联
DOI：
10.1097/psy.0000000000000595
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发表时间：
2018-07
影响因子：
3.3
通讯作者：
Cao Jia
中科院分区：
文献类型：
--
作者：
Zou Peng;Wang Xiaogang;Sun Lei;Chen Qing;Yang Huan;Zhou Niya;Chen Hongqiang;Zhang Guowei;Ling Xi;Wang Zhi;Gao Jianfang;Mo Min;Huang Linping;Peng Kaige;Chen Sheng;Cui Zhihong;Liu Jinyi;Ao Lin;Cao Jia
目的行为和心理社会因素与精液质量下降有关。然而，抑郁症和体力活动（PA）与精液质量的关系仍不清楚。方法于2013年6月对587名中国男大学生进行了问卷调查。参与者完成了一份评估生活方式因素的问卷，Zung自评抑郁量表和三个与PA相关的项目。他们接受了体格检查，并提供了精液样本和生殖激素（睾酮、雌激素、孕酮、卵泡刺激素、黄体生成素和催乳素）的血液样本。结果抑郁得分高的男性（n = 63，10.7%）精子密度较低（M（SD）= 66.9（74.5）对72.6（56.9）[106/ml]，p = 0.043）和总精子数（M（SD）= 241.6（299.7）对257.0（204.0）[106]，p = 0.024）。PA水平低的参与者（n = 99，16.9%）的总精子数（M（SD）= 204.4（153.7）vs 265.8（225.8）[106/ml]，p = 0.017）低于活动水平较高的参与者。在调整了潜在的混杂因素后，抑郁症男性的精子浓度比非抑郁症男性低18.90%（95%置信区间[CI] = 1.14%-33.47%），精子总数比非抑郁症男性低21.84%（95% CI = 3.39%-36.90%）。PA水平低的男性精子总数比体力活动参与者低23.03%（95%CI = 2.80%-46.89%）。检测到抑郁症和PA对精子浓度的相互作用（p = .033）。抑郁和PA与生殖激素无显著相关性（p > 0.05）。结论抑郁和低PA水平与精液质量水平降低有关，这可能对生殖健康有影响。
Objective Behavioral and psychosocial factors have been associated with a decline of the quality of semen. However, the relationship of depression and physical activity (PA) with semen quality remains unclear. Methods Data were obtained from 587 young male Chinese college students in June 2013. Participants completed a questionnaire assessing life-style factors, the Zung self-rated depression scale, and three items related to PA. They underwent a physical examination and provided a semen sample and a blood sample for reproductive hormones (testosterone, estrogen, progesterone, follicle-stimulating hormone, luteinizing hormone, and prolactin). Results Men with high depression scores (n = 63, 10.7%) had lower sperm concentration (M (SD) = 66.9 (74.5) versus 72.6 (56.9) [106/ml], p = .043) and total sperm count (M (SD) = 241.6 (299.7) versus 257.0 (204.0) [106], p = .024) than nondepressed men. Participants with low PA levels (n = 99, 16.9%) had lower total sperm count (M (SD) = 204.4 (153.7) versus 265.8 (225.8) [106/ml], p = .017) than participants with higher activity levels. After adjusting for potential confounders, depressed men had 18.90% (95% confidence interval [CI] = 1.14%–33.47%) lower sperm concentration and 21.84% (95% CI = 3.39%–36.90%) lower total sperm count than nondepressed men. Men with low PA levels had 23.03% (95% CI = 2.80%–46.89%) lower total sperm count than physically active participants. An interaction effect between depression and PA on sperm concentration was detected (p = .033). There were no significant associations of depression and PA with reproductive hormones (p > .05). Conclusions Depression and low levels of PA are associated with lower levels of semen quality, which may have implications for reproductive health.
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DOI：
10.1136/jfprhc-2011-100276
发表时间：
2013-04-01
影响因子：
--
作者：
Li, Ying;Li, Yafei;Cao, Jia
通讯作者：
Cao, Jia
DOI：
10.1038/sj.bdj.2012.909
发表时间：
2012-10
期刊：
BDJ
影响因子：
--
作者：
通讯作者：
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影响因子：
6.1
作者：
M. Fukuda;K. Fukuda;T. Shimizu;Wakako Yomura;Seiitsu Shimizu
通讯作者：
M. Fukuda;K. Fukuda;T. Shimizu;Wakako Yomura;Seiitsu Shimizu
影响因子：
6.7
作者：
Robert M. Levin;Jay D. Amsterdam;Andrew Winokur;Alan J. Wein
通讯作者：
Robert M. Levin;Jay D. Amsterdam;Andrew Winokur;Alan J. Wein
影响因子：
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作者：
E. Carlsen;A. Giwercman;N. Keiding;N. Skakkebæk
通讯作者：
E. Carlsen;A. Giwercman;N. Keiding;N. Skakkebæk