Portable infusion pumps in ambulatory cancer chemotherapy
Portable infusion pumps in ambulatory cancer chemotherapy
复制标题
便携式输液泵在门诊癌症化疗中的应用
作者：
T. Plasse;T. Ohnuma;H. Bruckner;K. Chamberlain;Terry Mass;J. F. Holland
57名接受化疗的成人患者接受了133次输液治疗，使用的是便携式输液泵AS*2F，Cormed ML6-4，以及后者的两个早期版本，Sigmamotor ML6-2和ML6-3。98次输液在动态基础上进行。14例经外周静脉插管输液，115例经中心静脉插管输液，4例经动脉内输液。在127次可评估的输液中，65次在计划比率的5%内完成，87次在计划比率的10%内完成；住院和门诊输液的结果相似。Cormed ML6-4泵在可靠性上与自动注射器相当，但在患者喜好方面优于自动注射器。没有危险的快速给药的例子。唯一严重的导管并发症是1例插入锁骨下导管后的气胸和1例使用Broviac导管的白细胞减少患者的蜂窝织炎。除3名患者外，所有患者都倾向于门诊治疗而不是住院治疗。门诊治疗每天的费用比住院治疗低约300美元。
Fifty‐seven adult patients receiving chemotherapy were treated with a total of 133 infusions using portable user‐worn infusion pumps, the Autosyringe AS*2F, Cormed ML6–4, and two earlier versions of the latter, the Sigmamotor ML6–2 and ML6–3. Ninety‐eight infusions were given on an ambulatory basis. Fourteen infusions were given through peripheral venous catheters, 115 through central venous catheters, and four intra‐arterially. Of 127 evaluable infusions, 65 were completed within 5% and 87 within 10% of the planned rate; results are similar for both inpatient and outpatient infusions. The Cormed ML6–4 pumps was equal to the Autosyringe AS*2F in reliability but superior to the latter in patient preference. There were no instances of dangerously rapid administration of the drug. The only serious catheter complications were a pneumothorax after insertion of a subclavian catheter in one patient and cellulitis in a leukopenic patient with a Broviac catheter. All but three patients preferred outpatient therapy to hospitalization. Outpatient therapy costs about $300 per day less than in‐hospital treatment.