Autoimmune hypophysitis: expanding the differential diagnosis to CTLA-4 blockade.
Autoimmune hypophysitis: expanding the differential diagnosis to CTLA-4 blockade.
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DOI：
10.1586/eem.09.37
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发表时间：
2009-11-01
影响因子：
3.2
通讯作者：
Caturegli, Patrizio
中科院分区：
文献类型：
--
作者：
Gutenberg, Angelika;Landek-Salgado, Melissa;Caturegli, Patrizio
自身免疫性垂体炎是一种日益被认识的疾病，可用于无功能垂体肿块的鉴别诊断。由于相似的临床表现和放射学体征，这些疾病的鉴别诊断具有挑战性。这篇综述描述了垂体炎和其他无功能垂体肿块的基本特征。它还强调了最近描述的垂体炎的一个特征：在接受消除细胞毒性 T 淋巴细胞抗原 4 功能的治疗的患者中，垂体炎的出现频率出乎意料地高。
Autoimmune hypophysitis is an increasingly recognized disorder that enters in the differential diagnosis of nonfunctioning pituitary masses. The differential diagnosis of these conditions is challenging because of similar clinical presentations and radiological signs. This review describes the essential features of hypophysitis and the other nonfunctioning pituitary masses. It also emphasizes a recently described feature of hypophysitis: its appearance with unexpectedly high frequency in patients receiving treatments that abrogate the function of cytotoxic T lymphocyte antigen 4.