Chest High-resolution Computed Tomography Findings in 601 Patients with Inflammatory Bowel Diseases
Chest High-resolution Computed Tomography Findings in 601 Patients with Inflammatory Bowel Diseases
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DOI：
10.1016/j.acra.2017.10.010
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发表时间：
2018-04-01
影响因子：
4.8
通讯作者：
Mori, Hiromu
中科院分区：
文献类型：
--
作者：
Sato, Haruka;Okada, Fumito;Mori, Hiromu
基本原理和目标：炎症性肠病的肺部受累可能反映了胃肠道和支气管树的共同胚胎起源。没有研究比较溃疡性结肠炎（UC）和克罗恩病（CD）之间的肺部高分辨率计算机断层扫描（HRCT）结果。本研究旨在评估肺部HRCT表现与炎症性肠病活动性之间的关系，并比较UC和CD之间的HRCT表现。材料和方法：我们回顾性地确定了601例连续患者（350例UC和251例CD），他们在2004年4月至2016年4月期间在我们的机构进行了胸部HRCT检查。实质异常，淋巴结肿大，胸腔积液进行了评估HRCT。结果：167例（94名男性，73名女性;年龄12-86岁，平均：47.2岁）UC和93例（61名男性，32名女性;年龄12-71岁，平均：37.9岁）CD患者胸部HRCT异常结果。UC和CD的HRCT表现主要包括小叶中心结节（分别为49.1%和45.2%）和支气管壁增厚（分别为31.7%和54.8%）。HRCT结果与疾病活动性之间无相关性。CD患者的支气管壁增厚明显高于UC患者（P
Rationale and Objectives: Pulmonary involvement in inflammatory bowel disease may reflect the common embryonic origin of the gastrointestinal tract and the bronchial tree. No studies have compared pulmonary high-resolution computed tomography (HRCT) findings between ulcerative colitis (UC) and Crohn disease (CD). This study aimed to assess the relationship between pulmonary HRCT findings and inflammatory bowel disease activity and to compare HRCT findings between UC and CD.Materials and Methods: We retrospectively identified 601 consecutive patients (350 with UC and 251 with CD) who had undergone chest HRCT examinations at our institutions between April 2004 and April 2016. Parenchymal abnormalities, enlarged lymph nodes, and pleural effusion were evaluated on HRCT.Results: One hundred sixty-seven patients (94 men, 73 women; aged 12-86 years, mean: 47.2 years) with UC and 93 patients (61 men, 32 women; aged 12-71 years, mean: 37.9 years) with CD had abnormal findings on chest HRCT. The HRCT findings of UC and CD mainly consisted of centrilobular nodules (in 49.1% and 45.2% of cases, respectively) and bronchial wall thickening (in 31.7% and 54.8%, respectively). There was no relationship between HRCT findings and disease activity. Bronchial wall thickening was significantly more frequent in patients with CD than in those with UC (P