Carbonate-radical-anions, and not hydroxyl radicals, are the products of the Fenton reaction in neutral solutions containing bicarbonate
Carbonate-radical-anions, and not hydroxyl radicals, are the products of the Fenton reaction in neutral solutions containing bicarbonate
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DOI：
10.1016/j.freeradbiomed.2018.11.015
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发表时间：
2019-02-01
影响因子：
7.4
通讯作者：
Meyerstein, Dan
中科院分区：
文献类型：
--
作者：
Illes, Erzsebet;Mizrahi, Amir;Meyerstein, Dan
芬顿反应，Fe(H2O)(6)(2+) + H2O2 -> 氧化产物，作为氧化应激的主要原因，在生物学和高级氧化过程中具有重要意义。通常认为中心点 OH 是芬顿反应的产物。本文提出的结果指出，中心点 OH 确实是酸性溶液中 [Fe(H2O)(6)(2+)] > [H2O2] 的氧化产物； Fe-aq(IV)在中性溶液中是活性氧化产物；在微酸性溶液中，[H2O2] > [Fe(H2O)(6)(2+)] 形成中心点 OH 和 Fe-aq(IV) 的混合物。然而，即使在低浓度下，即在生理条件下，CO3 中心点- 也是含有 HCO3- 的中性溶液中的活性氧化产物。讨论了对我们理解高级氧化过程中氧化应激和催化氧化的起源的影响。
The Fenton reaction, Fe(H2O)(6)(2+) + H2O2 -> Oxidizing product, is of major importance in biology as the major cause of oxidative stress, and in advanced oxidation processes. It is commonly assumed that center dot OH is the product of the Fenton reaction. The results presented herein point out that center dot OH is indeed the oxidizing product in acidic solutions for [Fe(H2O)(6)(2+)] > [H2O2]; Fe-aq(IV) is the active oxidizing product in neutral solutions; in slightly acidic solutions for [H2O2] > [Fe(H2O)(6)(2+)] a mixture of center dot OH and Fe-aq(IV) is formed. However CO3 center dot- is the active oxidizing product in neutral solutions containing HCO3- even at low concentrations, i.e. under physiological conditions. The implications to our understanding of the origins of oxidative stress and of catalytic oxidations in advanced oxidation processes are discussed.