Laparoscopic myomectomy: a 6-year follow-up single-center cohort analysis of fertility and obstetric outcome measures

Laparoscopic myomectomy: a 6-year follow-up single-center cohort analysis of fertility and obstetric outcome measures
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DOI:
10.1007/s00404-014-3155-2
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发表时间:
2014-07-01
影响因子:
2.6
通讯作者:
Runnebaum, Ingo Bernard
Runnebaum, Ingo Bernard
中科院分区:
医学3区
文献类型:
--
作者:
Bernardi, Tina Sybille;Radosa, Marc Philipp;Runnebaum, Ingo Bernard

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旨在评估长期随访期间腹腔镜子宫肌瘤切除术 (LM) 后的生育能力、妊娠和分娩结局。在这项单中心回顾性观察研究中,分析了 59 名 23-42 岁、有生育意愿、在 2001 年 1 月至 2006 年 12 月期间因症状性子宫肌瘤接受 LM 并随后在我院分娩的女性的数据。平均随访时间为 73.55 几个月后,LM 后受孕率为 68%。在所有妊娠 (n = 55) 中,流产 (n = 16) 的比例在 LM 后 (24%) 低于 LM 前 (43%)。三十九例 (46%) 分娩是初次剖腹产 (CS)。由于患者的意愿、胎盘并发症和子宫破裂(UR)而进行CS。在所有阴道分娩试验中,分娩成功率为 62%。在所有妊娠中,UR 和胎盘并发症的发生率分别为 10% 和 13%。在我们的队列中,LM 降低了流产率并增加了 CS 率。 UR 风险可能受到缝合技术、切除的肌瘤的大小和位置的影响。
To evaluate fertility, pregnancy and delivery outcomes after laparoscopic myomectomy (LM) during long-term follow-up.In this single-center retrospective observational study, data were analyzed from 59 women aged 23-42 years with the desire to have children and who underwent LM for symptomatic uterine leiomyoma between January 2001 and December 2006 and subsequently delivered at our hospital.During a mean follow-up period of 73.55 months, the post-LM conception rate was 68 %. The proportion of miscarriages (n = 16) among all pregnancies (n = 55) was lower after (24 %) than before (43 %) LM. Thirty-nine (46 %) deliveries were primary cesarean sections (CSs). CS was performed due to patients' preference, placental complications, and uterine rupture (UR). Labor was successful in 62 % of all vaginal delivery trials. UR and placental complications occurred in 10 and 13 % of all pregnancies, respectively.LM reduced the abortion rate and increased the CS rate in our cohort. UR risk may have been affected by suturing technique, the size and location of myomas removed.