A review of the MAFF Optimal Nutrition Status research programme: folate, iron and copper
A review of the MAFF Optimal Nutrition Status research programme: folate, iron and copper
复制标题
MAFF 最佳营养状况研究计划回顾：叶酸、铁和铜
作者：
J. Buttriss;J. Hughes
摘要目的：目的是对英国政府的一项研究计划“最佳营养状况”中进行的研究进行严格评估，并将这项工作的结果置于国际研究工作的背景下，以协助政策制定者和顾问。该计划涉及九种营养素；这里报告了其中三项的研究结果：叶酸/叶酸、铁和铜。设计：为了进行审查，研究人员可以访问项目产生的所有未发表的进度报告，这些报告已提交给官员。总体评估标准是研究计划产生的信息是否可以被视为与设定特定微量营养素的最佳膳食需求直接相关的可靠实验数据。然而，研究结果还根据具体的科学标准进行了评估，这些科学标准涉及对所审查的每种营养素的生物利用度、相互作用、功能标记物的发展以及新陈代谢的个体间差异的理解。结果：审查结果表明，英国政府的研究计划确实正在解决许多重要问题，并且这项工作正在为全世界就这一重要主题开展的整体研究工作做出贡献。结论：在确定不同亚人群的最佳摄入量之前，仍然需要解决许多主要问题。文件中总结了这些优先事项。
Abstract Objective: The objective was to conduct a critical appraisal of research conducted within one of the UK government's research programmes, Optimal Nutrition Status, and to place the findings of this work in the context of the international research effort, to assist policy makers and advisers. Nine nutrients are addressed within the programme; the findings for three of these are reported here: folate/folic acid, iron and copper. Design: To conduct the review, the researchers had access to all unpublished progress reports, submitted to officials, arising from the projects. The overall assessment criterion was whether the information generated by the research programme could be regarded as reliable experimental data of direct relevance to setting optimal dietary requirements for the particular micronutrients. However, findings were also assessed against specific scientific criteria concerning understanding of the bioavailability, interactions, development of functional markers and inter-individual variations in metabolism, for each of the nutrients scrutinised. Results: The results of the review indicated that many important questions are indeed being addressed by the UK government's research programme, and that the work is contributing to the overall research effort being conducted world-wide on this important subject. Conclusions: Many major questions still need to be addressed before it will be possible to identify optimal intakes for various sub-populations. These priorities are summarised in the paper.
影响因子：
10.3
作者：
Freudenheim, JL;Marshall, JR;Graham, S
通讯作者：
Graham, S
铁的摄入量和结直肠癌的风险。
DOI：
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发表时间：
1996
期刊：
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
影响因子：
--
作者：
Wurzelmann,JI;Silver,A;Schreinemachers,DM;Sandler,RS;Everson,RB
通讯作者：
Everson,RB