Spatial and temporal variability in schistosome cercarial density detected by mouse bioassays in village irrigation ditches in Sichuan, China

Spatial and temporal variability in schistosome cercarial density detected by mouse bioassays in village irrigation ditches in Sichuan, China
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DOI:
10.4269/ajtmh.2004.71.554
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发表时间:
2004-11-01
影响因子:
3.3
通讯作者:
Qiu, DC
Qiu, DC
中科院分区:
医学4区
文献类型:
--
作者:
Spear, RC;Zhong, B;Qiu, DC

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在2001年感染季节,采用小鼠生物测定法测定了四川省西南部5个村庄灌溉沟渠内血吸虫尾蚴密度的时空变异。方差分析表明,大约一半的变异是由村庄和村庄内的地点造成的,空气温度、每周平均降雨量或进行生物测定的感染季节的月份几乎没有贡献。这些数据的地点特异性变异性表明,如果不考虑与水接触地点的子宫颈密度变化,流行病学研究在检测水接触强度对人类寄生虫负担的影响方面通常能力较低。
A mouse bioassay was used monthly over the infection season of 2001 to determine the temporal and spatial variability of schistosome cercarial density in irrigation ditches in five villages in southwestern Sichuan Province in the People's Republic of China. Analysis of variance showed that approximately half of the variability was due to the village and site within the village, with little contribution from air temperature, weekly average rainfall, or the month within the infection season in which the bioassay was performed. The location-specific variability in these data suggest that epidemiologic studies will generally have low power to detect the influence of water-contact intensity on human parasite burden without taking account of variations in cercarial density at sites of water contact.