Longitudinal Studies of Diurnal Variations in Depression: A Sample of 643 Patient Days
Longitudinal Studies of Diurnal Variations in Depression: A Sample of 643 Patient Days
复制标题
抑郁症昼夜变化的纵向研究：643 个患者日的样本
DOI：
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发表时间：
1973
影响因子：
10.5
通讯作者：
R. Fieve
中科院分区：
文献类型：
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作者：
F. Stallone;G. Huba;W. Lawlor;R. Fieve
长期以来，症状强度的日变化一直被认为是抑郁症的一个特征，并且在该疾病的临床描述中一直占有突出地位。早晨抑郁症的恶化通常与内源性抑郁症有关，而晚上的恶化则被描述为反应性或神经性抑郁症的特征（Kiloh和Garside, 1963; Winokur， Clayton和Reich， 1969）。然而，尽管人们普遍认为昼夜节律模式具有诊断相关性，但对这些模式的系统研究却很少。
Diurnal variations in symptom intensity have long been recognized as a characteristic feature of depression, and have always had a prominent place in clinical descriptions of the illness. A worsening of depression in the morning has classically been associated with endogenous depression, while a worsening in the evening has been described as characteristic of reactive or neurotic depression (Kiloh and Garside, 1963; Winokur, Clayton and Reich, 1969). Yet, in spite of the widely held belief of the diagnostic relevance of diurnal patterns, little systematic research on these patterns has been reported.