Preparation and Characterization of Tau Oligomer Strains.
Preparation and Characterization of Tau Oligomer Strains.
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Tau 寡聚物菌株的制备和表征。
DOI：
10.1007/978-1-4939-7816-8_9
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发表时间：
2018
期刊：
影响因子：
--
通讯作者：
Kayed,Rakez
中科院分区：
文献类型：
--
作者：
Sengupta,Urmi;Carretero-Murillo,Mariana;Kayed,Rakez
An increasing number of studies have demonstrated the existence of multiple conformational entities of tau, as have been observed for prion protein. We have developed and optimized techniques to isolate and study oligomeric tau strains both in vitro and ex vivo. Moreover, we have modified protocols that demonstrate the seeding properties of oligomeric tau strains that are capable of propagating in vivo. These methods and protocols are explained in this chapter.
