Cytotoxic iridoid aldehydes from Taiwanese Viburnum luzonicum
Cytotoxic iridoid aldehydes from Taiwanese Viburnum luzonicum
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DOI：
10.1248/cpb.53.125
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发表时间：
2005-01-01
影响因子：
1.7
通讯作者：
Esumi, T
中科院分区：
文献类型：
--
作者：
Fukuyama, Y;Minoshima, Y;Esumi, T
从采自台湾高雄的芦荟(Viburnum Luzonicum)干叶的甲醇提取物中分离得到4个含(E)-或(Z)-对香豆酰基的环烯醚醛，其结构经波谱分析得到确证。化合物1-3对HeLa S3癌细胞具有中等的抑制活性。
Four new iridoid aldehydes bearing (E)- or (Z)-p-coumaroyl group, luzonial A (1), luzonial B (2), luzonidial A (3), and luzonidial B (4), were isolated from a methanol extract of the dried leaves of Viburnum luzonicum collected in Kaoshiung, Taiwan and their structures were elucidated by analysis of spectroscopic data. Compounds 1-3 exhibited moderate inhibitory activity against HeLa S3 cancer cells.