Evaluation of coronary flow reserve in hypertensive patients by dipyridamole transesophageal Doppler echocardiography
Evaluation of coronary flow reserve in hypertensive patients by dipyridamole transesophageal Doppler echocardiography
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DOI：
10.1016/s0002-9149(00)00919-x
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发表时间：
2000-08-01
影响因子：
2.8
通讯作者：
Elhendy, A
中科院分区：
文献类型：
--
作者：
Hamouda, MS;Kassem, HK;Elhendy, A
本研究评价了高血压伴和不伴左室肥厚患者的冠状动脉血流储备（CFR）。采用经食管多普勒超声心动图对15例正常人（I组）、21例无左室肥厚的高血压患者（II组）和27例左室肥厚的高血压患者（III组）的CFR进行了评估。所有高血压患者主诉典型心绞痛，冠状动脉造影正常。将样本体积放置在左冠状动脉主干和左前降支的分叉处。在静息状态、潘生丁输注后2分钟和静脉注射氨茶碱后2分钟评价冠状动脉血流速度。以双嘧达莫与静息时舒张期和收缩期峰值流速的比值作为CFR的指标。III组舒张期峰值流速比显著低于I组和II组（分别为1.6 ± 0.2、2.7 ± 0.4和2.1 ± 0.2，p
This study evaluates the coronary flow reserve (CFR) in hypertensive patients with and without left ventricular (LV) hypertrophy. CFR was assessed by transesophageal Doppler echocardiography in 15 normal subjects (group I), 21 hypertensive patients without LV hypertrophy (group II), and 27 hypertensive patients with LV hypertrophy (group III). All hypertensive patients were complaining of typical anginal pain and had normal coronary angiograms. The sample volume was placed at the bifurcation of the left main and left anterior descending coronary arteries. Coronary blood flow velocities were evaluated at rest, 2 minutes after dipyridamole infusion, and 2 minutes after intravenous aminophylline. The ratios of dipyridamole to rest peak diastolic and systolic velocities were considered as indexes of CFR. Peak diastolic velocity ratio was significantly lower in group III than in groups I and II (1.6 +/- 0.2 2.7 +/- 0.4, and 2.1 +/- 0.2, respectively p