CLINICAL COURSE AND SURGICAL PROGNOSIS OF 33 CASES OF INTRACRANIAL EPIDERMOID TUMORS
CLINICAL COURSE AND SURGICAL PROGNOSIS OF 33 CASES OF INTRACRANIAL EPIDERMOID TUMORS
复制标题
DOI：
10.1227/00006123-198904000-00013
复制
发表时间：
1989-04-01
期刊：
影响因子：
4.8
通讯作者：
TAKAKURA, K
中科院分区：
文献类型：
--
作者：
YAMAKAWA, K;SHITARA, N;TAKAKURA, K
分析了过去25年中治疗的33例颅内表皮样肿瘤的临床表现、与手术范围相关的复发率和长期生存率。表皮样瘤引起各种症状，尤其是桥小脑角（15例），其中4例（23.5%）观察到症状短暂缓解。鞍上区和第三脑室部位从首发症状到手术的平均时间（平均11个月）比其他部位（平均7年）短得多。28例（84.9%）肿瘤全切除或次全切除。大部分患者术后能独立生活（93.1%）。随访29例，复发7例，复发时间平均为8年10个月（第1 ~第2次手术）和12年6个月（第2 ~第3次手术）。肿瘤复发的患者成功治疗，即使在第二次或第三次手术后也观察到良好的功能预后。20年生存率为92.8%（Kaplan-Meier法）。
Thirty-three cases of intracranial epidermoid tumors treated during the past 25 years were analyzed with regard to clinical manifestations, recurrence rates related to the extent of surgery, and long-term survival rates. Epidermoid tumors caused various symptoms, especially in the cerebellopontine angle (15 cases), of which a transient remission of symptoms was observed in 4 cases (23.5%). The average time from initial symptoms to surgery was much shorter in suprasellar region and third ventricular locations (average of 11 months) than in other locations (average of 7 years). In 28 patients (84.9%), the tumor was removed totally or subtotally. Most of the patients could lead an independent and useful life after operation (93.1%). Among the 29 patients in a long-term follow-up survey, seven tumors recurred after an average interval of 8 years and 10 months (from the first to second operation) and 12 years and 6 months (from the second to third operation). Patients with recurrent tumors were successfully treated, and excellent functional prognosis was observed even after the second or third operation. The 20-year survival rate was 92.8% (Kaplan-Meier method).