CIRCULATORY CHANGES IN REPRODUCTIVE TISSUES OF EWES DURING PREGNANCY
CIRCULATORY CHANGES IN REPRODUCTIVE TISSUES OF EWES DURING PREGNANCY
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DOI：
10.1159/000301658
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发表时间：
1974-01-01
期刊：
影响因子：
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通讯作者：
BATTAGLIA, FC
中科院分区：
文献类型：
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作者：
ROSENFELD, CR;MORRISS, FH;BATTAGLIA, FC
应用放射性核素标记微球技术，对24只妊娠38~141日龄母羊的生殖器官血流进行了测定。术后4~7d将微球注入未麻醉动物的左心室内，同时在双侧子宫动脉用电磁探头连续记录子宫血流量。有黄体卵巢的血流量在妊娠早期最大，且大于无黄体卵巢。在胎盘生长期(40~90天)，胎盘血流量从∼30增加到∼300ml/m in。在妊娠的最后50天，胎盘重量下降，而胎盘血流量继续上升，近期达到∼1500毫升/分钟。胎儿体重和胎盘血流量的增长曲线相似，但早期胎盘血流量的增加比胎儿体重的增加更快。因此，妊娠早期每克胎儿胎盘血流量(∼)为9ml/m in·g，高于近月(∼0.25m l/m in·g)。在双胞胎妊娠中，每个胎儿的胎盘获得的血流量都比同龄的单胎胎盘小。直到最后60d，乳房血流量没有变化，从∼10增加到∼200ml/m in。这一现象与乳房重量增加和胎盘血流量最终进行性增加相吻合。
The blood flows to reproductive organs were measured by means of radionuclide-labeled microspheres in 24 pregnant ewes with gestational ages ranging from 38 to 141 days. The microspheres were injected in the left ventricle of the non-anesthetized animal 4–7 days after surgery and while uterine blood flow was recorded continously by means of electromagnetic probes on both uterine arteries. The blood flow to ovaries with corpus luteum was maximum in early pregnancy and greater than in ovaries without corpus luteum. Placental blood flow increased from ∼30 to ∼300 ml/min during the stage of placental growth (40–90 days). In the last 50 days of pregnancy placental weight declined, whereas placental flow continued to rise and attained ∼1,500 ml/min near term. The growth curves of fetal weight and placental blood flow followed a similar pattern, but the early increase in placental flow was more rapid than the increase in fetal weight. Hence placental flow per gram of fetus was larger in early pregnancy (∼9 ml/min·g) than near term (∼0.25 ml/min·g). In twin pregnancies the placenta of each fetus received a smaller blood flow than the placenta of a singleton of comparable age. Mammary blood flow demonstrated no change until the last 60 days, when it increased from ∼10 to ∼200 ml/min. This phenomenon coincided with an increase in mammary weight and the final progressive increase of placental blood flow.