High-Turnover Supramolecular Catalysis by a Protected Ruthenium(II) Complex in Aqueous Solution
High-Turnover Supramolecular Catalysis by a Protected Ruthenium(II) Complex in Aqueous Solution
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DOI：
10.1021/ja205257x
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发表时间：
2011-08-10
影响因子：
15
通讯作者：
Raymond, Kenneth N.
中科院分区：
文献类型：
--
作者：
Brown, Casey J.;Miller, Gregory M.;Raymond, Kenneth N.
报道了一种能够进行高转化率催化的超分子催化剂的设计。将钌(II)催化剂掺入水溶性超分子组装体中，赋予催化烯丙醇异构化的能力。催化剂通过主体内部的隔离来防止分解，但在主体内的限制范围内保留其催化活性。这种主客体复合物是一种独特的活性超分子催化剂，能够进行 > 1000 次周转。
The design of a supramolecular catalyst capable of high-turnover catalysis is reported. A ruthenium(II) catalyst is incorporated into a water-soluble supramolecular assembly, imparting the ability to catalyze allyl alcohol isomerization. The catalyst is protected from decomposition by sequestration inside the host but retains its catalytic activity with scope governed by confinement within the host. This host-guest complex is a uniquely active supramolecular catalyst, capable of > 1000 turnovers.