ORAL FLUORESCEIN ANGIOGRAPHY - REASSESSMENT OF ITS RELATIVE SAFETY AND EVALUATION OF OPTIMUM CONDITIONS WITH USE OF CAPSULES
ORAL FLUORESCEIN ANGIOGRAPHY - REASSESSMENT OF ITS RELATIVE SAFETY AND EVALUATION OF OPTIMUM CONDITIONS WITH USE OF CAPSULES
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DOI：
10.1136/bjo.74.8.458
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发表时间：
1990-08-01
影响因子：
4.1
通讯作者：
ROSEN, ES
中科院分区：
文献类型：
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作者：
WATSON, AP;ROSEN, ES
静脉注射荧光素进行眼底血管造影时，轻微不良反应的发生率较高（21%），但严重（危及生命）反应的发生率极低（0.05%）。无过敏史的患者可能会在没有任何征兆的情况下发生严重反应。目前尚无口服荧光素引起严重反应的报道，轻微的不良反应也不常见。进行了一项研究以确定口腔荧光素血管造影的最佳条件。事实证明，胶囊比溶液更方便摄入荧光素。 25 毫克/公斤体重的剂量可在 75% 的患者中产生高质量的血管造影照片。 40分钟和60分钟后拍摄眼底可获得最佳照片。
Injection of fluorescein intravenously for fundal angiography is associated with a high incidence of minor adverse effects (21%) but a very low incidence of serious (life threatening) reactions (0.05%). A serious reaction may occur without warning in a patient with no history of atopy. There are no reports of oral fluorescein causing a serious reaction, and minor adverse effects are uncommon. A study was undertaken to determine optimum conditions for oral fluorescein angiography. Capsules proved more convenient than a solution for ingestion of fluorescein. A dose of 25 mg/kg body weight produced good quality angiograms in 75% of the patients. The best pictures were obtained by photographing the fundus after 40 and 60 minutes.