Computed tomography assessment of pelvic bone density: Associations with age and pelvic fracture in motor vehicle crashes.
Computed tomography assessment of pelvic bone density: Associations with age and pelvic fracture in motor vehicle crashes.
复制标题
骨盆骨密度的计算机断层扫描评估：与年龄和机动车碰撞中骨盆骨折的关联。
DOI：
10.1016/j.aap.2023.107291
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发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Stitzel,JoelD
中科院分区：
文献类型：
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作者：
Weaver,AshleyA;Ronning,IsaacN;Armstrong,William;Miller,AnnaN;Kiani,Bahram;ShaynMartin,R;Beavers,KristenM;Stitzel,JoelD
机动车碰撞（MVC）乘员常规进行计算机断层扫描（CT）以筛选内部损伤，并且该CT可以被利用来机会性地导出骨矿物质密度（BMD）。本研究旨在开发和验证一种方法来测量骨盆骨密度在CT扫描没有一个幻影，并检查骨盆骨密度与年龄和骨盆骨折的发病率在严重受伤的MVC乘员的碰撞损伤研究和工程网络（CIREN）的研究。使用45次定量CT扫描和骨校准体模，验证了无体模肌肉脂肪校准技术测量骨盆BMD。然后，该技术被用来测量骨盆骨密度从CT扫描的252 CIREN占用者（年龄16岁以上）在额叶MVC谁持续腹部或骨盆损伤。分析骨盆骨密度与年龄和骨盆骨折发生率的关系。在验证组中，基于体模的校准与无体模的肌肉脂肪校准在髂前上级棘（ASIS; R2= 0.95，p < 0.001）和髂嵴（R2= 0.90，p < 0.001）产生相似的BMD值。对16-89岁的150名女性和102名男性Ciren居住者进行了骨盆骨密度测定，其中25%的居住者患有骨盆骨折。ASIS和髂嵴的BMD随年龄增长而下降（p< 0.001）。例如，髂嵴BMD平均每十年降低25 mg/cm 3。骨盆骨折患者每10岁髂嵴骨密度下降率比非骨盆骨折患者多7.6 mg/cm 3。研究结果表明，骨盆骨密度可能是一个贡献的危险因素，骨盆骨折的MVC。
Motor vehicle crash (MVC) occupants routinely get a computed tomography (CT) scan to screen for internal injury, and this CT can be leveraged to opportunistically derive bone mineral density (BMD). This study aimed to develop and validate a method to measure pelvic BMD in CT scans without a phantom, and examine associations of pelvic BMD with age and pelvic fracture incidence in seriously injured MVC occupants from the Crash Injury Research and Engineering Network (CIREN) study. A phantom-less muscle-fat calibration technique to measure pelvic BMD was validated using 45 quantitative CT scans with a bone calibration phantom. The technique was then used to measure pelvic BMD from CT scans of 252 CIREN occupants (ages 16+) in frontal MVCs who had sustained either abdominal or pelvic injury. Pelvic BMD was analyzed in relation to age and pelvic fracture incidence. In the validation set, phantom-based calibration vs. phantom-less muscle-fat calibration yielded similar BMD values at the anterior superior iliac spine (ASIS; R2= 0.95,p< 0.001) and iliac crest (R2= 0.90,p< 0.001). Pelvic BMD was measured in 150 female and 102 male CIREN occupants aged 16–89, and 25% of these occupants sustained pelvic fracture. BMD at the ASIS and iliac crest declined with age (p< 0.001). For instance, iliac crest BMD decreased an average of 25 mg/cm3per decade of age. The rate of iliac crest BMD decline was 7.6 mg/cm3more per decade of age in occupants with pelvic fracture compared to those not sustaining pelvic fracture. Findings suggest pelvic BMD may be a contributing risk factor for pelvic fracture in MVCs.