Hazardous events associated with impaired olfactory function
Hazardous events associated with impaired olfactory function
复制标题
DOI：
10.1001/archotol.130.3.317
复制
发表时间：
2004-03-01
影响因子：
--
通讯作者：
Costanzo, RM
中科院分区：
文献类型：
--
作者：
Santos, DV;Reiter, ER;Costanzo, RM
目的：评估嗅觉功能受损患者发生嗅觉相关危险事件的风险。设计：回溯性队列研究。背景：以大学为基础的嗅觉和味觉障碍诊所。患者：共有445名患者在1983至2001年间接受嗅觉测试。干预：患者访谈、嗅觉测试。主要观察指标：(1)嗅觉相关危险事件的发生频率，包括烹饪事件(如烧锅或锅)、未发现的火灾、未检测到的气体泄漏和摄入变质的食物或有毒物质；(2)嗅觉功能水平(嗅觉障碍；重度、中度或轻度嗅觉障碍；结果：嗅觉测试显示76%的患者有不同程度的嗅觉障碍；30%的患者有完全嗅觉障碍。37%的嗅觉受损患者经历了至少1次与嗅觉相关的危险事件，但只有19%的非嗅觉受损患者经历了至少1次与嗅觉相关的危险事件。在受损患者报告的危险事件中，与烹饪有关的事件最常见，占45%，摄入变质的食物(25%)，无法检测到气体泄漏(23%)，以及无法闻到火味(7%)报告的频率较低。危险事件发生频率与嗅觉损害程度呈显著正相关(Cochran-Armitage趋势检验，P
Objective: To evaluate the risk of olfactory-related hazardous events in patients with impaired olfactory function.Design: Retrospective cohort study.Setting: A university-based clinic for smell and taste disorders.Patients: A total of 445 patients who underwent olfactory testing between 1983 and 2001.Interventions: Patient interview, olfactory testing.Main Outcome Measures: (1) Frequency of olfactory-related hazardous events including cooking incidents (ie, burning pots or pans), undetected fires, undetected gas leaks, and ingestion of spoiled foods or toxic substances; (2) level of olfactory function (anosmia; severe, moderate, or mild hyposmia; or normosmia) as determined by olfactory testing.Results: Olfactory testing revealed that 76% of patients had some degree of impairment; 30% had complete anosmia. Thirty-seven percent of patients with olfactory impairment but only 19% of patients without impairment experienced at least I olfactory-related hazardous event. Of the hazardous events reported by impaired patients, cooking-related incidents were most common, representing 45%, with ingestion of spoiled food (25%), inability to detect a gas leak (23%), and inability to smell a fire (7%) reported less frequently. There was a significant correlation between frequency of hazardous events and degree of olfactory impairment (Cochran-Armitage trend test, P