PROPORTION OF DISEASE CAUSED OR PREVENTED BY A GIVEN EXPOSURE, TRAIT OR INTERVENTION
PROPORTION OF DISEASE CAUSED OR PREVENTED BY A GIVEN EXPOSURE, TRAIT OR INTERVENTION
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DOI：
10.1093/oxfordjournals.aje.a121617
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发表时间：
1974-01-01
影响因子：
5
通讯作者：
MIETTINE.OS
中科院分区：
文献类型：
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作者：
MIETTINE.OS
两个流行病学参数的结构进行了探讨。一个是“病因分数“，与风险增加的标志物有关，它是可归因于标志物和/或与之相关的因素的疾病比例;另一个是“预防分数“，相当于风险降低的标志物。结果表明，这两个参数依赖于-在不同的方式-在疾病的情况下，标记的频率，并在“标准化发病率比”的标记。这些参数的点估计通常是直接的，特别是在病例对照研究中。
The structures of two epidemiologic parameters are explored. One, the “etiologic fraction, ” relates to markers of increased risk, and it is the proportion of disease attributable to the marker and/or to factors associated with it. The other, the “prevented fraction, ” is the equivalent of this for a marker of reduced risk. It is shown that both parameters depend—in different ways—-on the frequency of the marker among cases of the disease, and on the “standardized morbidity ratio” for those with the marker. Point estimation of these parameters is often straight-forward, particularly in case-control studies.