Effector-independent Representations Guide Sequential Target Selection Biases in Action
Effector-independent Representations Guide Sequential Target Selection Biases in Action
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DOI：
10.1162/jocn_a_02102
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发表时间：
2024-03-01
影响因子：
3.2
通讯作者：
Song，Joo-Hyun
中科院分区：
文献类型：
--
作者：
O'Bryan，Sean R.;Moher，Jeff;Song，Joo-Hyun
先前的研究表明，对最近选择的目标特征的自动注意力偏差会在动作和感知之间转移，甚至会在逐个试验的基础上在不同的效应器（如眼睛和手）之间转移。尽管这些发现表明效应器之间选择历史的共同神经表示，但有关最近选择的目标特征的信息在重叠与不同的大脑区域中编码的程度尚不清楚。使用功能磁共振成像和启动弹出任务，参与者选择不可预测的，独特的彩色目标之间的同质干扰，通过达到或扫视，我们发现，颜色启动是由共享的，效应器独立的基本表示最近的选择历史。与以前的工作相一致，我们发现，顶内沟（IPS）通常激活的试验中，目标颜色被切换相对于那些重复的颜色，然而，背前沟表现出效应器特异性激活颜色启动。通过多体素交叉分类分析，我们进一步证明了IPS和内侧颞叶中的细粒度活动模式以效应器无关的方式编码有关选择历史的信息，因此在到达选择期间对活动模式进行训练的ROI特定模型可以预测在扫视选择期间当前试验中颜色是否重复或切换，反之亦然。值得注意的是，IPS和内侧颞叶的模型泛化性能也跟踪了两种类型动作的行为启动敏感性的个体差异。这些结果代表了第一步，以澄清经验驱动的选择偏见的背景下，需要多个动作的协调的神经基板。
Previous work shows that automatic attention biases toward recently selected target features transfer across action and perception and even across different effectors such as the eyes and hands on a trial-by-trial basis. Although these findings suggest a common neural representation of selection history across effectors, the extent to which information about recently selected target features is encoded in overlapping versus distinct brain regions is unknown. Using fMRI and a priming of pop-out task where participants selected unpredictable, uniquely colored targets among homogeneous distractors via reach or saccade, we show that color priming is driven by shared, effector-independent underlying representations of recent selection history. Consistent with previous work, we found that the intraparietal sulcus (IPS) was commonly activated on trials where target colors were switched relative to those where the colors were repeated; however, the dorsal anterior insula exhibited effector-specific activation related to color priming. Via multivoxel cross-classification analyses, we further demonstrate that fine-grained patterns of activity in both IPS and the medial temporal lobe encode information about selection history in an effector-independent manner, such that ROI-specific models trained on activity patterns during reach selection could predict whether a color was repeated or switched on the current trial during saccade selection and vice versa. Remarkably, model generalization performance in IPS and medial temporal lobe also tracked individual differences in behavioral priming sensitivity across both types of action. These results represent a first step to clarify the neural substrates of experience-driven selection biases in contexts that require the coordination of multiple actions.