Biosensors based on one-dimensional nanostructures
Biosensors based on one-dimensional nanostructures
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DOI：
10.1039/c1jm10521c
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发表时间：
2011-01-01
影响因子：
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通讯作者：
Star, Alexander
中科院分区：
文献类型：
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作者：
Feigel, Ian Matthew;Vedala, Harindra;Star, Alexander
在过去的十年中，一维纳米结构（1D-NS）已经被研究用于检测生物分子。这些纳米级材料的直径与单个生物分子的大小相当，具有高灵敏度的优点。在这篇专题文章中，我们讨论了使用1D-NS的不同生物传感技术，即电学，电化学，光学和机械方法，重点关注这些技术的进步。讨论了1D-NS的各种合成和功能化方法的优缺点，以及生物传感器器件的制备过程。本文主要介绍了近十年来基于一维纳米结构的蛋白质和DNA传感器的研究进展，并对未来的发展进行了展望
Over the past decade, one-dimensional nanostructures (1D-NS) have been studied for the detection of biological molecules. These nanometre-scale materials, with diameters comparable to the size of individual biomolecules, offer the advantage of high sensitivity. In this feature article we discuss different techniques of biosensing using 1D-NS, namely electrical, electrochemical, optical, and mechanical methods, with a focus on the advancement of these techniques. Advantages and disadvantages of various synthesis and functionalization methods of 1D-NS, as well as biosensor device fabrication procedures are discussed. The main focus of this review is to demonstrate the progress of protein and DNA sensors based on 1D-NS over the past decade, and in addition we present an outlook