Relationship of plasma cholesteryl ester transfer protein to HDL cholesterol - Studies in normotriglyceridemia and moderate hypertriglyceridemia
Relationship of plasma cholesteryl ester transfer protein to HDL cholesterol - Studies in normotriglyceridemia and moderate hypertriglyceridemia
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DOI：
10.1161/01.atv.16.12.1430
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发表时间：
1996-12-01
影响因子：
8.7
通讯作者：
Patsch, JR
中科院分区：
文献类型：
--
作者：
Foger, B;Ritsch, A;Patsch, JR
为了评估胆固醇酯转移蛋白（CETP）对人体HDL浓度的独立影响，我们测量了16名健康、血脂正常男性和23名中度原发性高血脂男性的血脂、脂蛋白、口服脂肪负荷后的餐后脂血症、CETP质量和CETP、脂蛋白脂酶（LPL）和肝脂酶的活性。与对照组相比，高脂血症组空腹甘油三酯和餐后血脂升高，高密度脂蛋白胆固醇（HDL-C）降低（P
To evaluate the independent effect of cholesteryl ester transfer protein (CETP) on HDL concentrations in humans, we measured lipids, lipoproteins, postprandial lipemia after an oral fat load, CETP mass, and the activities of CETP, lipoprotein lipase (LPL), and hepatic lipase in 16 healthy, normotriglyceridemic men and in 23 men with moderate, primary hypertriglyceridemia on the American Heart Association Step I diet. Fasting triglycerides and postprandial lipemia were increased and HDL cholesterol (HDL-C) was decreased in hypertriglyceridemic men compared with control subjects (P