Generalized Vitiligo After Stem Cell Transplantation: A Case Report.
Generalized Vitiligo After Stem Cell Transplantation: A Case Report.
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DOI：
10.2147/ccid.s420342
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发表时间：
2023
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移植物抗宿主病（GVHD）是由供、受者之间的同种异体免疫反应引起的一种复杂的免疫介导的病理生理过程。无论急性还是慢性GVHD，皮肤受累都是最常见的，严重的皮肤损伤可导致永久性毁容，严重影响患者的长期生活质量。我们在此报告一位再生障碍性贫血患者接受异基因外周血造血干细胞移植后并发泛发性白癜风。
Graft versus host disease (GVHD) is a complex immune-mediated pathophysiological process, which is caused by allogenic immune reactions between donors and recipients. No matter ac-ute or chronic GVHD, skin involvement is the most common, severe skin damage can lead to permanent disfigurement, which seriously affects the long-term quality of life of patients. We herein report a patient with generalized vitiligo after allogeneic peripheral hematopoietic stem cell transplantation (allo-HSCT) for aplastic anemia.