Coffee and its effects on the immune system
Coffee and its effects on the immune system
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DOI：
10.1016/j.tifs.2021.06.023
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发表时间：
2021-06-19
影响因子：
15.3
通讯作者：
Sanlier, Nevin
中科院分区：
文献类型：
--
作者：
Acikalin, Busra;Sanlier, Nevin
背景：咖啡是自古以来全球消费量最大的饮料之一。在此之前，人们习惯于饮用咖啡，因为咖啡因的刺激作用和独特的味道。近年来，它已经不仅仅是一种含有刺激剂的热饮，并开始意识到其对健康的积极影响。具有抗氧化潜力的咖啡化合物可以列举为咖啡因、绿原酸、咖啡酸、香豆酸、烟酸、阿魏酸、胡芦巴碱、咖啡碱和咖啡豆酚。范围和方法：虽然据报道，咖啡会影响一系列慢性疾病，包括肥胖，癌症，神经退行性疾病和心血管疾病，这是由于咖啡因，绿原酸和二萜醇，它包含，并需要在这方面进行进一步的研究，咖啡也与降低自身免疫性疾病的风险有关。这篇综述旨在阐述咖啡消费与免疫系统之间的关系。主要调查结果和结论：此外，近年来人们强调，上述咖啡化合物由于其抗氧化和抗炎作用而刺激免疫系统。咖啡对免疫系统的积极影响源于咖啡因，绿原酸，咖啡豆，咖啡因和它含有的类似化合物。特别是咖啡因和多酚被认为是营养咖啡的主要成分，具有免疫调节特性，取决于每日消费剂量。
Background: Coffee is one of the beverages consumed the most worldwide since ancient times. Previously, coffee used to be consumed due to its stimulating effect stemming from caffeine and its distinctive taste. In recent years, it has gone beyond being just a hot drink containing stimulating agents and has started to be consumed with the awareness about its positive effects on health. The compounds of coffee bearing antioxidant potential can be listed as caffeine, chlorogenic acids, caffeic acid, coumaric acid, nicotinic acid, ferulic acid, trigonelline, cafestol, and kahweol. Scope and approach: While it is reported that coffee impacts a range of chronic diseases including obesity, cancer, neurodegenerative and cardiovascular diseases due to the caffeine, chlorogenic acids, and diterpenoid alcohol it contains and that further research is needed in this respect, coffee is also related to a reduced risk of autoimmune diseases. This review aims to elaborate on the relationship between coffee consumption and the immune system. Key findings and conclusions: In addition, it has been highlighted in recent years that the above-mentioned compounds of coffee stimulate the immune system thanks to their antioxidant and anti-inflammatory effects. The positive effects of coffee on the immune system stem from caffeine, chlorogenic acids, kahweol, cafestol and similar compounds it contains. Particularly caffeine and polyphenols are considered as the main agents nourishing coffee with immunomodulatory characteristics depending on the daily dose of consumption.