(±)-Perforison A, A Pair of New Chromone Enantiomers from Harrisonia perforata
(±)-Perforison A, A Pair of New Chromone Enantiomers from Harrisonia perforata
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DOI：
10.1177/1934578x1701200118
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发表时间：
2017-01
影响因子：
1.8
通讯作者：
Wen-Juan Yuan;Wen-Fen Gao;Jiahui Zhang;P. Cao;Yu Zhang;Duo-zhi Chen;Shun-Lin Li;Y. Di;X. Hao
中科院分区：
文献类型：
--
作者：
Wen-Juan Yuan;Wen-Fen Gao;Jiahui Zhang;P. Cao;Yu Zhang;Duo-zhi Chen;Shun-Lin Li;Y. Di;X. Hao
（+）- perforison A和(-)-perforison A是一种新的染色体对映体，与4种已知化合物一起，从穿孔哈里森（Harrisonia perforata）的叶和茎中分离得到。它们的结构和绝对构型是在广泛分析光谱数据和电子圆二色性（ECD）计算的基础上确定的。对这些化合物的体外细胞毒活性进行了评价，但没有显示出显著的活性。
(+)-Perforison A and (-)-perforison A, a new pair of chromone enantiomers, along with four known compounds, were isolated from the leaves and stems of Harrisonia perforata. Their structures and absolute configurations were determined on the basis of extensive analysis of spectroscopic data and electronic circular dichroism (ECD) calculations. The cytotoxic activities in vitro of these compounds were evaluated, but none showed significant activity.