Description of retention characteristics of calixarene-bonded stationary phases in dependence of the methanol content in the mobile phase.
Description of retention characteristics of calixarene-bonded stationary phases in dependence of the methanol content in the mobile phase.
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DOI：
10.1016/j.chroma.2009.07.004
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发表时间：
2009-08
期刊：
影响因子：
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通讯作者：
C. Schneider;T. Jira
中科院分区：
文献类型：
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作者：
C. Schneider;T. Jira
已知HPLC中的杯芳烃键合固定相与常规烷基键合相相比支持额外的相互作用（π-π相互作用、复合物构建相互作用）。因此，不能假定适用相同的保留机制，也不能以类似的方式预测保留。在这里，31个高度不同的分子结构的溶质已在不同的移动的流动相组成（0-98%（v/v）甲醇）进行了分析，以验证新的固定相的色谱行为，并测试所建立的模型预测保留因子的适用性。甲醇含量的变化的影响进行了讨论，为非极性，极性和离子溶质和它们的行为上的不同列类型的差异。此外，估计潜在的保留机制。
Calixarene-bonded stationary phases in HPLC are known to support additional interactions compared to conventional alkyl-bonded phases (π–π interactions, complex-building interactions). Thus it cannot be presumed that the same mechanisms of retention apply and that retention can be predicted in similar ways. Here 31 solutes of highly various molecular structures have been analysed at different mobile phase compositions (0–98% (v/v) methanol) in order to characterise the chromatographic behaviour of the novel stationary phases and to test the applicability of established models predicting retention factors. The influence of a change of the methanol content is discussed for non-polar, polar and ionic solutes and differences of their behaviour on the differing column types are shown. Additionally estimates about underlying retention mechanisms are given.