TBN-mediated regio- and stereoselective sulfonylation & oximation (oximosulfonylation) of alkynes with sulfonyl hydrazines in EtOH/H2O
TBN-mediated regio- and stereoselective sulfonylation & oximation (oximosulfonylation) of alkynes with sulfonyl hydrazines in EtOH/H2O
复制标题
TBN 介导的区域选择性和立体选择性磺酰化
DOI：
10.1039/c8gc02708k
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发表时间：
2019
期刊：
影响因子：
9.8
通讯作者：
Wang Zhiyong
中科院分区：
文献类型：
--
作者：
Wang Bin;Yan Zicong;Liu Liyan;Wang Jiawei;Zha Zhenggen;Wang Zhiyong
An alkyne difunctionalization cascade reaction was developed to generate α-sulfonylethanone oximes under metal-free conditions. The reaction features environmentally benign EtOH/H2O as a solvent, a broad substrate scope and easily scaled up for gram-scale synthesis. The reaction mechanism was illustrated with UPLC, GC-MS and UPLC-tof/MS.
