GASTROINTESTINAL-TRACT SYMPTOMS AND SELF-REPORTED ABUSE - A POPULATION-BASED STUDY
GASTROINTESTINAL-TRACT SYMPTOMS AND SELF-REPORTED ABUSE - A POPULATION-BASED STUDY
复制标题
DOI：
10.1016/0016-5085(94)90228-3
复制
发表时间：
1994-10-01
期刊：
影响因子：
29.4
通讯作者：
MELTON, LJ
中科院分区：
文献类型：
--
作者：
TALLEY, NJ;FETT, SL;MELTON, LJ
背景/目的：在门诊患者中，滥用药物与肠易激综合征（IBS）之间存在联系，但仍存在争议。没有基于人群的研究调查过这个问题。本研究的目的是确定代表性社区样本中滥用的普遍程度及其与症状的关系。方法：对明尼苏达州奥姆斯特德县30 ~ 49岁的居民按年龄和性别分层随机抽样，邮寄一份有效的自我报告症状问卷。虐待是根据标准公布的标准进行评估的。结果：在919名应答者（74%）中，任何虐待的年龄调整患病率在女性中为41%，在男性中为11%，导致年龄和性别调整患病率为26%。肠易激综合征、消化不良和频繁烧心症状分别为14%、23%和12%。肠易激综合征与性虐待、情感或言语虐待以及童年和成年期的虐待之间存在显著关联。同样，消化不良和胃灼热都与虐待显著相关。在人群中，31%的人因胃肠道症状去看过医生；那些在成年期和儿童期遭受虐待的人去看医生的几率最高。结论：自述虐待在中年被试中较为常见；那些报告滥用药物的人更有可能出现与肠易激综合征、消化不良或胃灼热一致的症状，并因肠道症状而去看医生。
Background/Aims: A link between abuse and irritable bowel syndrome (IBS) has been reported in outpatients but remains controversial. No population-based studies have investigated this issue. The aim of this study was to determine the prevalence of abuse and its association with symptoms in a representative community sample. Methods: An age- and sex-stratified random sample of residents of Olmsted County, Minnesota ranging in age from 30 to 49 years was mailed a valid self-report symptom questionnaire. Abuse was assessed by standard published criteria. Results: Of the 919 responders (74%), the age-adjusted prevalence of any abuse was 41% in women and 11% in men, resulting in an age- and sex-adjusted prevalence of 26%. Symptoms of IBS, dyspepsia, and frequent heartburn were reported by 14%, 23%, and 12%, respectively. There was a significant association between IBS and sexual abuse, emotional or verbal abuse, and abuse in childhood and adulthood. Similarly, dyspepsia and heartburn were both significantly associated with abuse. In the population, 31% had visited a physician for gastrointestinal symptoms; the odds of visiting a physician were highest in those reporting abuse in adulthood and childhood. Conclusions: Self-reported abuse is common in middle-aged subjects; those who report abuse are more likely to have symptoms consistent with IBS, dyspepsia, or heartburn and to visit a physician for bowel symptoms.