The effects of amygdala lesions on conditioned stimulus-potentiated eating in rats

The effects of amygdala lesions on conditioned stimulus-potentiated eating in rats
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DOI:
10.1016/s0031-9384(02)00688-1
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发表时间:
2002-05-01
影响因子:
2.9
通讯作者:
Gallagher, M
Gallagher, M
中科院分区:
医学3区
文献类型:
--
作者:
Holland, PC;Petrovich, GD;Gallagher, M

文献摘要

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对照大鼠和杏仁中央核神经毒性损伤的大鼠在呈现先前与食物配对的条件刺激(CS)期间比在未配对的CS期间摄入更多的食物。无论食物是放在原来的位置还是放在不同的位置,这种增强都会发生。相比之下,杏仁基底外侧核神经毒性损伤的大鼠没有表现出进食条件增强的证据。这些结果是在从这些杏仁核区到参与摄食的其他脑区的解剖学投影的背景下考虑的,以及杏仁核亚区域在获得条件反射中的激励价值方面的作用。(C)2002 Elsevier Science Inc.保留所有权利。
Both control rats and rats with neurotoxic lesions of the amygdala central nucleus ate more food during presentations of a conditioned stimulus (CS) previously paired with food than during an unpaired CS. This potentiation occurred regardless of whether the food was presented in its usual place or in a different location. By contrast, rats with neurotoxic lesions of basolateral amygdala showed no evidence for conditioned potentiation of eating. These results are considered in the context of anatomical projections from these amygdalar areas to other brain regions involved in feeding, and the role of amygdala subregions in the acquisition of motivational value in conditioning. (C) 2002 Elsevier Science Inc. All rights reserved.