Foveal Microstructure and Visual Acuity after Retinal Detachment Repair Imaging Analysis by Fourier-Domain Optical Coherence Tomography
Foveal Microstructure and Visual Acuity after Retinal Detachment Repair Imaging Analysis by Fourier-Domain Optical Coherence Tomography
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DOI：
10.1016/j.ophtha.2008.10.001
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发表时间：
2009-03-01
期刊：
影响因子：
13.7
通讯作者：
Tano, Yasuo
中科院分区：
文献类型：
--
作者：
Wakabayashi, Taku;Oshima, Yusuke;Tano, Yasuo
目的：评价孔源性视网膜脱离（rrd）解剖成功修复后眼球中央凹的显微结构变化。设计：回顾性、连续、观察性病例系列。参与者：51例连续患者的53只眼睛，在解剖成功的手术修复后，有黄斑的rrd（15只眼睛）或没有黄斑的rrd（38只眼睛）。方法：采用傅里叶域光学相干断层扫描（FD-OCT）评价术后中央凹显微结构。评估术后最佳矫正视力（BCVA）与中央凹显微结构的相关性。主要观察指标：FD-OCT获得的中央凹微结构图像与当日测量的BCVA图像。结果：术后平均10.3 +/- 7.3个月（范围1-25）获得FD-OCT图像。中央凹解剖异常33眼（62%）；23眼（43%）光感受器内外段连接破坏，其中9眼（39%）外限制膜（ELM）破坏；视网膜下积液6眼（11%），视网膜前膜12眼（23%），黄斑囊样水肿2眼（4%）。光感受器IS/OS连接的破坏仅在黄斑关闭的眼睛中观察到，而其他显微结构异常在黄斑打开和黄斑关闭的眼睛中都观察到。术前无黄斑眼，术后BCVA与术后FD-OCT检测光感受器IS/OS和ELM信号完整性显著相关(r = 0.805
Purpose: To evaluate foveal microstructural changes in eyes with anatomically successful repair of rhegmatogenous retinal detachments (RRDs).Design: Retrospective, consecutive, observational case series.Participants: Fifty-three eyes of 51 consecutive patients with macula-on RRDs (15 eyes) or macula-off RRDs (38 eyes) after anatomically successful surgical repair.Methods: A microscopic fundus examination was conducted followed by Fourier-domain optical coherence tomography (FD-OCT) to assess the postoperative foveal microstructure. The correlation between the postoperative best-corrected visual acuity (BCVA) and microstructural findings at the fovea was evaluated.Main Outcome Measures: Images of the foveal microstructure obtained by FD-OCT and the BCVA measured on the same day.Results: We obtained FD-OCT images a mean of 10.3 +/- 7.3 months (range, 1-25) postoperatively. Foveal anatomic abnormalities were detected in 33 eyes (62%); disruption of the junction between the photoreceptor inner and outer segments (IS/OS) in 23 eyes (43%), of which 9 eyes (39%) had a disrupted external limiting membrane (ELM); residual subretinal fluid in 6 eyes (11%), epiretinal membranes in 12 eyes (23%), and cystoid macular edema in 2 eyes (4%). Disruption of the photoreceptor IS/OS junction was observed only in macula-off eyes, whereas other microstructural abnormalities were observed in both macula-on and macula-off eyes. In preoperative macula-off eyes, the postoperative BCVA was significantly correlated with the integrity of the photoreceptor IS/OS and ELM signals detected by FD-OCT postoperatively (r = 0.805; P