XANTHOMATOUS GIANT CELL TUMORS ARISING IN SOFT TISSUE: Report of An Instance of Malignant Growth
XANTHOMATOUS GIANT CELL TUMORS ARISING IN SOFT TISSUE: Report of An Instance of Malignant Growth
复制标题
软组织中出现的黄色巨细胞瘤：恶性生长实例的报告
DOI：
10.1001/archsurg.1949.01240040918012
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发表时间：
1949
影响因子：
--
通讯作者：
S. Perlow
中科院分区：
文献类型：
--
作者：
M. Kobak;S. Perlow
关于发生于软组织的黄色瘤样巨细胞瘤的恶性性质一直存在相当大的争议。在肌腱和腱鞘中观察到的病变中，Fleissig 1指出没有转移性生长的真实记录。Gomori [2]和Bussebaum [3]以及Berger [4]在对这个问题进行更一般性的评价时也得出了类似的结论。然而，有各种迹象表明这种性质的肿瘤可能是恶性的。Berger 4引用了一个例子，其中在起源于大腿的生长中注意到局部侵入性。Tourneux 5报告了Gaudiani记录的一例巨细胞瘤转移至局部淋巴结。同样，他引用了多尔描述的一个病例，多尔治疗了食指上的一个肿瘤，诊断为骨髓瘤。这个肿块被切除，但局部复发，然后明显扩散。组织学
THERE has been considerable controversy about the malignant nature of xanthomatous giant cell tumors arising in soft tissues. Of the lesions noted in tendons and tendon sheaths Fleissig 1 stated that there is no authentic record of metastatic growth. A similar conclusion has likewise been reached by Gomori 2 and Bussebaum 3 and by Berger 4 in a more general appraisal of the problem. There have been, however, various indications that tumors of this nature may be malignant. Berger 4 cited an example in which local invasive qualities were noted in a growth originating in the thigh. Tourneux 5 reported an instance recorded by Gaudiani wherein a giant cell tumor metastasized to the regional lymph nodes. Similarly, he cited a case described by Dor, who treated a tumor on the index finger diagnosed as sarcoma myeloplaxes. This mass was excised, but it recurred locally and apparently then spread generally. Histologic