Close proximity to blast: No long-term or lasting effect on cognitive performance in service members with and without TBI during blast exposure.
Close proximity to blast: No long-term or lasting effect on cognitive performance in service members with and without TBI during blast exposure.
复制标题
近距离接触爆炸：在爆炸暴露期间，对有或没有 TBI 的服役人员的认知表现没有长期或持久的影响。
DOI：
10.1017/s1355617722000558
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发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Kennedy,JE
中科院分区：
文献类型：
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作者：
Lu,LH;Reid,MW;Troyanskaya,M;Scheibel,RS;Muncy,C;Kennedy,JE
目的：爆炸相关特征可能有助于战区部署期间持续的轻度创伤性脑损伤是否具有持久的认知影响。本研究旨在评估近距离爆炸暴露史（定义为30英尺以内的暴露）是否对现役和退役军人的认知结果有长期或持久的影响。方法100名参与者根据战斗部署期间的爆炸暴露史自述分为三组：47名近距离爆炸，14名非近距离爆炸，39名没有爆炸暴露的比较参与者。工作记忆、处理速度、语言学习/记忆和认知灵活性使用标准神经心理学测试进行评估。此外，通过自我报告测量评估战斗暴露和当前脑震荡后、创伤后应激、抑郁症状和头痛。组间差异的变量作为协变量进行控制。结果对家庭误差率进行Bonferroni校正后，各组间无差异；在工作记忆、处理速度、语言学习/记忆或认知灵活性方面，近距离爆炸组与非近距离爆炸组和对照组没有差异。控制协变量并没有改变这些结果。结论与其他组相比，没有证据表明近距离爆炸暴露史与认知能力下降有关。爆炸环境的有限特征，爆炸距离的自我报告，以及组内损伤严重程度的异质性是本研究的主要局限性。
ObjectiveBlast related characteristics may contribute to the diversity of findings on whether mild traumatic brain injury sustained during war zone deployment has lasting cognitive effects. This study aims to evaluate whether a history of blast exposure at close proximity, defined as exposure within 30 feet, has long-term or lasting influences on cognitive outcomes among current and former military personnel.MethodOne hundred participants were assigned to one of three groups based on a self-report history of blast exposure during combat deployments: 47 close blast, 14 non-close blast, and 39 comparison participants without blast exposure. Working memory, processing speed, verbal learning/memory, and cognitive flexibility were evaluated using standard neuropsychological tests. In addition, assessment of combat exposure and current post-concussive, posttraumatic stress, and depressive symptoms, and headache was performed via self-report measures. Variables that differed between groups were controlled as covariates.ResultsNo group differences survived Bonferroni correction for family-wise error rate; the close blast group did not differ from non-close blast and comparison groups on measures of working memory, processing speed, verbal learning/memory, or cognitive flexibility. Controlling for covariates did not alter these results.ConclusionNo evidence emerged to suggest that a history of close blast exposure was associated with decreased cognitive performance when comparisons were made with the other groups. Limited characterization of blast contexts experienced, self-report of blast distance, and heterogeneity of injury severity within the groups are the main limitations of this study.