Enhancing HIV medication adherence in India.

Enhancing HIV medication adherence in India.
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DOI:
10.1177/1545109712446177
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发表时间:
2013-09-01
影响因子:
--
通讯作者:
Weiss, Stephen M
Weiss, Stephen M
中科院分区:
其他
文献类型:
--
作者:
Jones, Deborah;Sharma, Aman;Weiss, Stephen M

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BACKGROUND: This pilot study evaluated an intervention designed to enhance adherence among those new to antiretroviral therapy.METHODS: Participants (n = 80) were recruited from a hospital clinic in Chandigarh, India, and randomized to a 3-month group intervention or individual enhanced standard of care followed by crossover of condition and assessed over 6 months. Adherence was measured by prescription refill, pill count, and self-report.RESULTS: At baseline, 56% of group condition (immediate intervention) and 54% of individual condition (delayed intervention) participants were nonadherent by pill count and 23% of group and 26% of individual condition participants self-reported skipping medication at least once over the last 3 months. From the postintervention to long-term follow-up, adherence in the group condition (immediate intervention) improved in comparison with adherence in the individual condition (delayed intervention; chi(2) = 5.67, P = .02).CONCLUSIONS: Results support the use of interventions early in treatment to provide information and social support to establish long-term healthy adherence behaviors.