Localized nonlinear modes in microbubbles under the action of ultrasound
Localized nonlinear modes in microbubbles under the action of ultrasound
复制标题
超声作用下微泡中的局域非线性模式
DOI：
10.1109/ultsym.2016.7728853
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发表时间：
2016
期刊：
影响因子：
--
通讯作者：
V. Sánchez
中科院分区：
文献类型：
--
作者：
S. Dos Santos;N. Jiménez;V. Sánchez
在特定的超声激励下，造影剂微泡发生非线性振荡。考虑到现象的大小和复杂性，需要昂贵而复杂的实验和/或模拟。为了克服这一点，已经提出并验证了类比的使用。为了在宏观尺度上对气泡超声振动进行再定标，对一系列耦合振子进行了优化。表面模振荡的参数振荡(驱动特性)表现出模式混合行为，包括当驱动频率略低于色散曲线边缘时出现的本征局域模(ILM)。这一结果建议了一些优化的超声激励，以显示用于超声手术的超声造影剂(UCA)的局部声响应。在参数激励下，这种类比正确地描述了由于形状不稳定性而产生的气泡的表面模式。
Under specific ultrasound excitation, contrast microbubbles undergo nonlinear oscillations. Considering the size and the complexity of the phenomenon, expensive and complex experiments and/or simulations are required. To overcome this, the use of an analogy has been proposed and validated. A chain of coupled oscillators has been optimized in order to re-scale the bubble ultrasonic oscillation at the macroscopic scale. The parametric oscillation (characteristic of the driving) responsible of the surface mode oscillations exhibit mode mixing behavior including intrinsic localized modes (ILM) that emerge when the frequency of the driving is slightly below the edges of the dispersion curves. This result suggests some optimized ultrasonic excitation in order to exhibit local acoustic response of ultrasound contrast agents (UCA) used for sonoporation. Under parametric excitation, this analogy correctly describes the surface modes of the bubble as a consequence of shape instability.
影响因子：
2.9
作者：
McDannold, Nathan;Vykhodtseva, Natalia;Hynynen, Kullervo
通讯作者：
Hynynen, Kullervo