NeuroCogFX -: A computer-based neuropsychological assessment battery for the follow-up examination of neurological patients
NeuroCogFX -: A computer-based neuropsychological assessment battery for the follow-up examination of neurological patients
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DOI：
10.1055/s-2006-932162
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发表时间：
2006-11-01
影响因子：
0.6
通讯作者：
Helmstaedter, C.
中科院分区：
文献类型：
--
作者：
Fliessbach, K.;Hoppe, C.;Helmstaedter, C.
许多神经治疗试验需要对认知功能进行纵向评估。一个理想的测试工具应该符合经典测试理论的标准，而且在管理和解释上应该是可重复的和经济的。我们开发了NeuroCogFX，一个计算机化的评估电池，根据这些标准。NeuroCogFX包括短期记忆，工作记忆，心理速度，选择性注意力，语言和图形记忆和语言流畅性的子测试（平均持续时间：25分钟）。从244名无神经或精神疾病史的受试者（年龄范围16 - 75岁）中获得了与神经系统相关的规范性数据。42名受试者在平均8周（范围：6 - 10周）后重新测试，以评估重测信度和培训效果。重测信度在所有子测验中均为中等大小，除了一个子测验，范围从r（12）= 0.5到r（12）= 0.7（2回检验：r（12）= 0.37）。对于结构验证NeuroCogFX管理，除了一个全面的神经心理学评估电池在一组40名健康受试者和42例慢性癫痫患者。该测试可以有效评估短期记忆，反应速度，记忆力和语言流畅性。NeuroCogFX是一种经济，足够可靠和有效的工具，用于对单个患者和研究组进行神经心理学随访检查，如果无法进行全面的神经心理学评估，则可以进行管理。
Many neurological therapeutic trials require a longitudinal assessment of cognitive functions. An ideal instrument for that purpose should be in accordance to the criteria of classical testing theory and, furthermore, it should be repeatable and economic in administration and interpretation. We developed NeuroCogFX, a computerized assessment battery, according to these criteria. NeuroCogFX comprises subtests for short term memory, working memory, psychomotor speed, selective attention, verbal and figural memory and verbal fluency (mean duration: 25 minutes). Age-related normative data was obtained from 244 subjects without history of neurological or psychiatric disease (age range 16 - 75 years). Forty-two subjects were re-tested after an average of 8 weeks (range: 6 - 10 weeks) in order to assess retest reliability and training effects. Retest-reliabilities were middle-sized in all but one subtest, ranging from r(12) = 0.5 to r(12) = 0.7 (2-back Test: r(12) = 0.37). For construct validation NeuroCogFX was administered in addition to a comprehensive neuropsychological assessment battery in a group of 40 healthy subjects and in 42 patients with chronic epilepsy. The test allows a valid assessment of short-term memory, reaction speed, memory and verbal fluency. NeuroCogFX is an economic, sufficiently reliable and valid instrument for the neuropsychological follow-up examination in single patients and study groups which can be administered if a comprehensive neuropsychological assessment is unavailable.