Phenotyping, Etiological Factors, and Biomarkers: Toward Precision Medicine in Autism Spectrum Disorders.

Phenotyping, Etiological Factors, and Biomarkers: Toward Precision Medicine in Autism Spectrum Disorders.
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DOI:
10.1097/dbp.0000000000000351
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发表时间:
2016-10
期刊:
Journal of developmental and behavioral pediatrics : JDBP
影响因子:
--
通讯作者:
MISSOURI AUTISM SUMMIT CONSORTIUM
MISSOURI AUTISM SUMMIT CONSORTIUM
中科院分区:
其他
文献类型:
--
作者:
Beversdorf DQ;MISSOURI AUTISM SUMMIT CONSORTIUM

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Despite the progress made in understanding the biology of autism spectrum disorder (ASD), effective biological interventions for the core symptoms remain elusive. Because of the etiological heterogeneity of ASD, identification of a “one-size-fits-all” treatment approach will likely continue to be challenging. A meeting was convened at the University of Missouri and the Thompson Center to discuss strategies for stratifying patients with ASD for the purpose of moving toward precision medicine. The “white paper” presented here articulates the challenges involved and provides suggestions for future solutions.