Acupuncture improves the emotion domain and lipid profiles in women with polycystic ovarian syndrome: a secondary analysis of a randomized clinical trial.
Acupuncture improves the emotion domain and lipid profiles in women with polycystic ovarian syndrome: a secondary analysis of a randomized clinical trial.
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DOI：
10.3389/fendo.2023.1237260
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发表时间：
2023
影响因子：
5.2
通讯作者：
中科院分区：
文献类型：
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作者：
本研究旨在通过对2012年7月6日至2015年10月7日进行的一项随机临床试验的二次分析，评估针灸对中国多囊卵巢综合征（PCOS）女性情绪领域和代谢参数的影响。在这项研究中，我们调查了针灸（458例患者）和假针灸（468例患者）对代谢参数，血清离子和所有与PCOS相关的生活质量量表评分的影响。患者的生活质量进行了评估，使用五个相关的量表，由研究助理，即PCOSQ，SF-36，ChiQOL，以及Zung-SAS和Zung-SDS。测定代谢参数和血清离子。针刺组在调整克罗米酚和生育结局后4个月的痤疮评分、AN、Hcy和LDL-C降低，脂蛋白α、Apo A1和Apo A1/Apo B水平升高（p< 0.05）。干预4个月后，针刺组SF-36总分、RP和RE评分、ChiQOL总分和情绪领域评分增加，PF和HT评分降低（校正后p< 0.05）。在假针刺中也观察到同样的变化。同时，针刺组干预后血清Ca、K、Cl水平升高（校正后p< 0.005）。HOMA-IR、MetS、FPG、FINS、HDL-C、TG、Apo B及血清P、Mg、Na水平无显著性差异。治疗后血压、生长激素、室性心动过速、SF、形体领域、精神领域无明显变化。针刺不仅能改善SF-36量表和ChiQOL量表的情绪变化，还能改善脂代谢，提示针刺可能与情绪变化和脂代谢有关。针刺还能调节血清Ca、K、Cl的变化。 ，标识符NCT 01573858。
This study aims to evaluate the effect of acupuncture on the emotion domain and metabolic parameters of Chinese women with polycystic ovarian syndrome (PCOS) by secondary analysis of a randomized clinical trial, conducted from 6 July 2012 to 7 October 2015. In this study, we investigated the effects of acupuncture (458 patients) and sham acupuncture (468 patients) on metabolic parameters, serum ions, and all quality-of-life scale scores related to PCOS. The quality of life of patients was evaluated using five relevant scales, operated by the research assistant, namely, PCOSQ, SF-36, and ChiQOL, as well as Zung-SAS and Zung-SDS. Metabolic parameters and serum ions were measured. A reduction in acne score, AN, Hcy, and LDL-C, and an increase in the level of lipoprotein α, Apo A1, and Apo A1/Apo B were observed in the acupuncture group after 4 months’ intervention after adjusting clomiphene and reproductive outcome (p< 0.05). An increase in SF-36 total scores, RP and RE scores, ChiQOL total scores, and emotion domain scores was observed in the acupuncture group after 4 months’ intervention, while PF and HT scores were decreased (adjusted p< 0.05). Those same changes were observed in sham acupuncture. Meanwhile, the serum levels of Ca, K, and Cl were elevated in the acupuncture group after the interventions (adjusted p< 0.005). There were no significant differences in HOMA-IR, MetS, FPG, FINS, HDL-C, TG, Apo B, and level of serum P, Mg, and Na. Also, no changes in BP, GH, VT, SF, physical form domain, and spirit domain were observed after treatment. Acupuncture can improve not only the emotional changes in SF-36 scores and ChiQOL scores, but also lipid metabolism, implying that it may have a correlation between emotional change and lipid metabolism. Furthermore, acupuncture can also regulate the changes of serum Ca, K, and Cl. , identifier NCT01573858.
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DOI：
10.1155/2013/527303
发表时间：
2013
期刊：
Evidence-based complementary and alternative medicine : eCAM
影响因子：
--
作者：
Kuang H;Li Y;Wu X;Hou L;Wu T;Liu J;Ng EH;Stener-Victorin E;Legro RS;Zhang H
通讯作者：
Zhang H
电针仪诱导的三维可视化通过PCOS大鼠的交感神经神经神经化激活了棕色脂肪组织。
影响因子：
4.9
作者：
Gao, Hongru;Tong, Xiaoyu;Hu, Wei;Wang, Yicong;Lee, Kuinyu;Xu, Xiaoqing;Shi, Jiemei;Pei, Zhenle;Lu, Wenhan;Chen, Yuning;Zhang, Ruonan;Wang, Zheyi;Wang, Ziyu;Han, Chengzhi;Wang, Yu;Feng, Yi
通讯作者：
Feng, Yi
影响因子：
4
作者：
Chang, Hui;Xie, Liangzhen;Wu, Xiaoke
通讯作者：
Wu, Xiaoke
影响因子：
15.1
作者：
Jung, Jeeyoun;Lee, So Min;Park, Ji-Yeun
通讯作者：
Park, Ji-Yeun
DOI：
10.1016/j.ejogrb.2012.03.023
发表时间：
2012-08-01
影响因子：
2.6
作者：
Li, Rong;Qiao, Jie;Wei, Zhaolian
通讯作者：
Wei, Zhaolian