Dermoscopic subpatterns of ashy dermatosis related to lichen planus.
Dermoscopic subpatterns of ashy dermatosis related to lichen planus.
复制标题
与扁平苔藓相关的灰皮肤病的皮肤镜亚型。
DOI：
10.1001/archdermatol.2009.300
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发表时间：
2010
影响因子：
--
通讯作者：
I. Zalaudek
中科院分区：
文献类型：
--
作者：
F. Vázquez;A. Vidal;I. Zalaudek
皮肤镜有助于鉴别持续时间较长的灰褐色皮肤病和色素沉着过度的扁平苔藓（LP）病变。图1A显示了一位67岁女性LP患者前臂的紫色丘疹和消退的棕色斑疹。前者的皮肤镜检查显示威克姆纹（WS）被毛细血管包围（图1B）。消退的病变显示无结构的棕色色素沉着，无粒度（图1C，箭头）。这种模式有利于一个短暂的临床过程，如图1D所示，它显示了色素沉着在不到1年的时间内消失。图2A显示了一名20岁女性的躯干，有LP病史，变色持续超过2年。图2B中的皮肤镜图像显示了WS。图2和D显示了退行性灰斑，其中颗粒状灰棕色点和小球（真皮噬黑素细胞）勾勒出WS或聚集在某些WS的凹陷中心（“灰洞”）。大量颗粒似乎表明病程较慢。这些病例表明，不同的皮肤镜模式代表非萎缩性，退行性LP。它们可能提示不同的临床过程。
D ERMOSCOPY AIDS IN DISTINGUISHING ASHY dermatosis and hyperpigmented lichen planus (LP) lesions that tend to persist for a longer period. Figure 1A shows a violaceous papule and regressing brown macules on the forearm of a 67-year-old woman with LP. Dermoscopy of the former reveals Wickham striae (WS) surrounded by capillaries (Figure 1B). Regressing lesions reveal a structureless brown pigmentation in the absence of granularity (Figure 1C, arrows). Such a pattern favors a transient clinical course, as demonstrated in Figure 1D, which shows the disappearance of pigmentation in less than 1 year. Figure2Ashowsthetrunkofa20-year-oldwomanwith a history of LP with discoloration persisting for more than 2 years. The dermoscopic image in Figure 2B shows WS. Figure2CandDreveal regressinggraymaculeswithgranular gray-brown dots and globules (dermal melanophages) outlining WS or clustered in the depressed centers of some WS (“ashy holes”). A large amount of granules appears to indicate a slower course. These cases demonstrate that differentdermoscopicpatternsarepresent innonatrophic, regressing LP. They likely suggest a different clinical course.