Perspectives on clinical magnetic particle imaging
Perspectives on clinical magnetic particle imaging
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DOI：
10.1515/bmt-2012-0064
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发表时间：
2013-12-01
影响因子：
1.7
通讯作者：
Rahmer, Juergen
中科院分区：
文献类型：
--
作者：
Borgert, Joern;Schmidt, Joachim D.;Rahmer, Juergen
在实现了世界上第一个临床前磁粒子成像（MPI）演示器之后，飞利浦现在正在实现世界上第一个全身临床原型，以证明MPI用于临床成像的可行性。在简要介绍了MPI成像的基本过程之后，本文概述了关键特性的决定因素，即，空间分辨率、采集速度、灵敏度和定量性，以及从临床前到临床仪器的按比例放大如何影响这些特性。此外，它是如何影响的方法以及硬件参数，如驱动场生成，选择和聚焦场生成的功率要求，以及MPI设备的接收链的设计的生理兼容性的这种规模。
After realizing the worlds' first preclinical magnetic particle imaging (MPI) demonstrator, Philips is now realizing the worlds' first whole-body clinical prototype to prove the feasibility of MPI for clinical imaging. After a brief introduction of the basic MPI imaging process, this contribution presents an overview on the determining factors for key properties, i.e., spatial resolution, acquisition speed, sensitivity, and quantitativeness, and how these properties are influenced by scaling up from preclinical to clinical instrumentation. Furthermore, it is discussed how this scale up affects the physiological compatibility of the method as well as hardware parameters such as power requirements for drive field generation, selection and focus field generation, and the design of the receive chain of the MPI device.