Somatosensory N250 and P300 during discrimination tasks
Somatosensory N250 and P300 during discrimination tasks
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DOI：
10.1016/s0167-8760(03)00021-7
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发表时间：
2003-06-01
影响因子：
3
通讯作者：
Wasaka, T
中科院分区：
文献类型：
--
作者：
Kida, T;Nishihira, Y;Wasaka, T
本研究采用事件相关电位（N250和P300）对三种不同类型的躯体感觉辨别任务（oddball任务）进行了研究。强（标准：90%）和弱（偏差：10%）的电刺激被随机传递到右正中神经的手腕，500毫秒恒定的刺激间隔。在被动情境中，受试者阅读一本自选书籍，忽略所有刺激（忽略条件）。其中一个活跃的情况是一个心理计数任务（计数条件），另一个需要按下一个按钮，以偏差刺激尽快（运动反应条件）。在主动注意条件下，偏离刺激能诱发N250-P300复合波，而在忽略条件下则不能。N250峰值振幅在计数和运动反应条件之间没有变化，而P300发生了变化。此外，N250潜伏期与反应时显著相关，而P300潜伏期与反应时不相关。这些结果表明，体感N250反映了一个注意的过程，这是有关的时间方面的行为反应。(C)2003 Elsevier Science B. V.保留所有权利。
We investigated the event-related potentials (N250 and P300) during three kinds of somatosensory discrimination tasks (oddball task). Strong (standard: 90%) and weak (deviant: 10%) electrical stimuli were randomly delivered to the right median nerve at the wrist with a 500-ms constant interstimulus interval. In a passive situation, subjects read a self-selected book, ignoring all stimuli (ignore condition). One of the active situations was a mental counting task (count condition), and another required pressing a button to deviant stimuli as quickly as possible (motor response condition). The N250-P300 complex was elicited by deviant stimuli in the active-attended situations, but not found in the ignore condition. The N250 peak amplitude was unchanged between the count and motor response conditions whereas P300 changed. In addition, the N250 latency significantly correlated with the reaction time, but the P300 latency did not. These results indicate that the somatosensory N250 reflects an attentive process which is related to the temporal aspect of behavioral response. (C) 2003 Elsevier Science B.V. All rights reserved.