Prevalence, Diagnosis and Management of Pancreatic Cystic Neoplasms: Current Status and Future Directions.
Prevalence, Diagnosis and Management of Pancreatic Cystic Neoplasms: Current Status and Future Directions.
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DOI：
10.5009/gnl15063
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发表时间：
2015-09-23
期刊：
影响因子：
3.4
通讯作者：
Farrell JJ
中科院分区：
文献类型：
--
作者：
Farrell JJ
胰腺囊性肿瘤的患病率不断增加，特别是在无症状的老年人中。尽管恶性肿瘤的总体风险非常低，但由于担心恶性肿瘤，这些胰腺囊肿的存在与很大程度的焦虑和进一步的医学检查有关。本综述讨论了不同的胰腺囊性肿瘤，并报告了基于临床特征和影像数据的诊断策略。根据最近修订的仙台指南，还讨论了最常见囊性肿瘤的手术和非手术治疗，特别是导管内乳头状粘液性肿瘤（IPMN；特别是分支导管变异型），这是最常偶然发现的病变。讨论了 IPMN 病理学、其发展为胰腺导管腺癌的风险、当前治疗指南的优缺点，以及超声内镜在确定癌症风险中的潜在作用。最后，讨论了手术治疗、胰腺囊肿监测策略以及未来可能的方向。
Cystic neoplasms of the pancreas are found with increasing prevalence, especially in elderly asymptomatic individuals. Although the overall risk of malignancy is very low, the presence of these pancreatic cysts is associated with a large degree of anxiety and further medical investigation due to concerns about malignancy. This review discusses the different cystic neoplasms of the pancreas and reports diagnostic strategies based on clinical features and imaging data. Surgical and nonsurgical management of the most common cystic neoplasms, based on the recently revised Sendai guidelines, is also discussed, with special reference to intraductal papillary mucinous neoplasm (IPMN; particularly the branch duct variant), which is the lesion most frequently identified incidentally. IPMN pathology, its risk for development into pancreatic ductal adenocarcinoma, the pros and cons of current guidelines for management, and the potential role of endoscopic ultrasound in determining cancer risk are discussed. Finally, surgical treatment, strategies for surveillance of pancreatic cysts, and possible future directions are discussed.
影响因子：
2
作者：
Lee LS;Clancy T;Kadiyala V;Suleiman S;Conwell DL
通讯作者：
Conwell DL