Gender differences in cardiovascular mortality by C-reactive protein level in the United States: Evidence from the National Health and Nutrition Examination Survey III
Gender differences in cardiovascular mortality by C-reactive protein level in the United States: Evidence from the National Health and Nutrition Examination Survey III
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DOI：
10.1016/j.ahj.2013.03.017
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发表时间：
2013-07-01
影响因子：
4.8
通讯作者：
Muennig, Peter
中科院分区：
文献类型：
--
作者：
Doran, Bethany;Zhu, Wenyi;Muennig, Peter
Background The association between C-reactive protein (CRP) and cardiovascular (CV) mortality by gender has not been previously described using a data set that is representative of the US population.Methods We used Cox proportional hazards models to explore gender differences in CRP-associated mortality via the National Health and Nutrition Examination Survey III 1988-1994 linked to the National Death Index with mortality follow-up through 2006. We examined CV mortality as well as all-cause mortality hazards.Results The final sample size included a total of 13,878 individuals (7,364 women and 6,514 men) with a median follow up of 18.2 years. All models controlled for race, age, smoking, high-density lipoprotein, hypertension, diabetes mellitus, waist circumference, and total cholesterol. Men with a CRP >3.0 mg/L relative to those with a CRP
