The Long-Term Outcomes of Prepubertal Depression and Internalizing Problems: A Scoping Review.
The Long-Term Outcomes of Prepubertal Depression and Internalizing Problems: A Scoping Review.
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青春期前抑郁症和内化问题的长期结果：范围界定审查。
DOI：
10.1097/hrp.0000000000000337
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发表时间：
2022-05-01
影响因子：
3.8
通讯作者：
Weissman, Myrna M.
中科院分区：
文献类型：
--
作者：
Sands, Adam;van Dijk, Milenna T.;Abraham, Eyal;Yangchen, Tenzin;Talati, Ardesheer;Weissman, Myrna M.
在参加这项活动后，学习者应该能够更好地：·讨论青春期前抑郁症是否与成年期抑郁症表现出纵向连续性。·总结现有文献中关于青春期前抑郁症和内化问题的成人情感和功能结果。青少年和年轻成年人发病的抑郁症是常见的，复发性的，并可能导致显着的困扰和心理社会损害的整个生命周期，但认识到青春期前的内化问题和抑郁症，沿着其患病率，临床过程，和长期的结果，仍然是难以捉摸的。研究青春期前抑郁症是否与成年期抑郁症表现出纵向连续性，并总结现有文献对青春期前抑郁症和内化问题的成人情感和功能结果。使用PubMed和PsycINFO对2000年至2020年期间发表的同行评审队列文章进行了范围审查。从4309篇识别的参考文献中，纳入了17篇文章。青春期前抑郁症增加了成年后抑郁症复发的风险，青春期前内化问题也有类似的发现。没有研究发现青春期前抑郁或内化问题可以预测成人药物滥用，也没有研究询问成人双相情感障碍的诊断。需要更多的研究来得出明确的结论，关于他们对其他精神病学，医学或心理社会结果的影响。回顾的研究提供了有限的证据表明，青春期前抑郁症的发病预测成人抑郁症。小的证据基础和异质性的方法评估可能会限制，但是，能够得出有意义的结论，青春期前发病的抑郁症的长期过程。需要设计良好的研究，在成年期进行更长时间的随访和多次评估，以澄清和评估青春期前抑郁症对成年健康和功能的潜在影响。随着最近启动的儿童纵向队列研究的样本进一步成熟，这些信息最终将变得可用。
After participating in this activity, learners should be better able to: • Discuss whether prepubertal depression shows longitudinal continuity with depression in adulthood. • Summarize existing literature on adult emotional and functional outcomes of prepubertal depression and internalizing problems. Adolescent- and young adult–onset depression are common, recurrent, and can cause significant distress and psychosocial impairment across the life span, but recognition of prepubertal internalizing problems and depression, along with their prevalence, clinical course, and long-term outcomes, remains elusive. To examine whether prepubertal depression, which can manifest differently from adult depression, shows longitudinal continuity with depression in adulthood, and to summarize existing literature on adult emotional and functional outcomes of prepubertal depression and internalizing problems. A scoping review was conducted for peer-reviewed cohort articles published between 2000 and 2020 using PubMed and PsycINFO. From 4309 identified references, 17 articles were included. Prepubertal depression confers increased risk of recurrence of depression in adulthood, with similar findings for prepubertal internalizing problems. No studies found prepubertal depression or internalizing problems predicting adult substance abuse, and no studies asked about adult bipolar diagnoses. More research is needed to draw clear conclusions regarding their implications for other psychiatric, medical, or psychosocial outcomes. The reviewed studies provide limited evidence that prepubertal depression onset predicts adult depression. The small evidence base and heterogeneous methodological assessments may limit, however, the ability to draw meaningful conclusions about the long-term course of prepubertal-onset depression. Well-designed studies with longer follow-up and multiple assessments in adulthood are needed to clarify and assess the potential effects of prepubertal depression on adult health and functioning. This information will eventually become available as the samples in recently initiated longitudinal cohort studies of children mature further.