Magnetic microsphere-based mixers for microdroplets
Magnetic microsphere-based mixers for microdroplets
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DOI：
10.1063/1.3072602
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发表时间：
2009-02-01
影响因子：
4.6
通讯作者：
Puri, Ishwar K.
中科院分区：
文献类型：
--
作者：
Roy, Tamal;Sinha, Ashok;Puri, Ishwar K.
虽然基于液滴的微流体系统具有优于传统流通装置的若干优点，但是在基于液滴的反应器内实现试剂之间的充分混合仍然具有挑战性。我们描述了一种主动混合方法的基础上磁搅拌的自组装链的磁性微球内的液滴，因为这些搅拌器经历一个旋转磁场。我们测量的水溶性染料在液滴中的混合方面的一个尺寸的混合参数的字段，转速，流体粘度，和微球负载参数变化。这些表明，混合速率在取决于操作条件的临界梅森数处具有最大值。
While droplet-based microfluidic systems have several advantages over traditional flow-through devices, achieving adequate mixing between reagents inside droplet-based reactors remains challenging. We describe an active mixing approach based on the magnetic stirring of self-assembled chains of magnetic microspheres within the droplet as these stirrers experience a rotating magnetic field. We measure the mixing of a water-soluble dye in the droplet in terms of a dimensional mixing parameter as the field-rpm, fluid viscosity, and microsphere loading are parametrically varied. These show that the mixing rate has a maximum value at a critical Mason number that depends upon the operating conditions.