First Description of KPC-2-Producing Pseudomonas putida in Brazil
First Description of KPC-2-Producing Pseudomonas putida in Brazil
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DOI：
10.1128/aac.05268-11
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发表时间：
2012-04-01
影响因子：
4.9
通讯作者：
Morais, Marcia M. C.
中科院分区：
文献类型：
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作者：
Almeida, Anna C. S.;Vilela, Marinalda A.;Morais, Marcia M. C.
这项工作报告了在巴西发现的首例产KPC-2的恶臭假单胞菌分离株（PP 36）。PP 36分离株对除多粘菌素B外的所有测试的抗菌剂具有抗性。除了发现的bla（KPC-2）基因外，遗传分析还显示存在1类整合子，其中含有dhfrXVb基因和新的等位基因E1 A-6，该等位基因编码利福平抗性。这些元件存在于IncFI 65-kb质粒中。
This work reports the identification of the first case of a KPC-2-producing Pseudomonas putida isolate (PP36) in Brazil. The PP36 isolate was resistant to all the antimicrobials tested except polymyxin B. In addition to the discovered bla(KPC-2) gene, genetic analysis showed the presence of a class 1 integron containing the dhfrXVb gene and the new allele arr-6, which codes for resistance to rifampin. These elements were found in an IncFI 65-kb plasmid.