Prevalence of various comorbidities among veterans with chronic kidney disease and its comparison with other datasets
Prevalence of various comorbidities among veterans with chronic kidney disease and its comparison with other datasets
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DOI：
10.3109/0886022x.2015.1117924
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发表时间：
2016-01-01
期刊：
影响因子：
3
通讯作者：
Arora, Pradeep
中科院分区：
文献类型：
--
作者：
Patel, Nilang;Golzy, Mojgan;Arora, Pradeep
慢性肾脏病（CKD）与各种合并症之间存在复杂的相互关系。本研究的目的是描述CKD退伍军人中各种合并症的患病率，并将其与其他数据集进行比较，如肾脏早期评估计划（KEEP），国家健康和营养检查调查（NHANES）和医疗保险。2007年（2007年1月1日至2007年12月31日）至少接受过一次门诊访视的患者被纳入研究（n = 75，787）。通过肾脏疾病饮食改良（MDRD）研究方程估计肾小球滤过率（eGFR）。CKD患病率的计算基于至少间隔3个月的一个或两个血清肌酐值。获得人口统计学数据，包括年龄、性别、种族、体重、身高和体重指数（BMI）。还根据问题列表中的ICD 9代码收集了各种合并症的患病率。退伍军人中CKD的患病率为47.3%，远高于美国人口的估计值。CKD患者更可能患有任何血管疾病（36.89% vs. 14.87%）、糖尿病（34.18% vs. 17.83%）、高血压（86.65% vs. 57.56%）和癌症（18.69% vs. 9.23%）。无论年龄大小，CKD退伍军人的血管疾病患病率都要高得多。与其他数据集相比，患有CKD的老年退伍军人的冠状动脉疾病，外周血管疾病和癌症的患病率要高得多。CKD是一种日益严重的地方病，伴随着高频率的慢性疾病。公共卫生资源应用于CKD的早期识别和风险调整。
Chronic kidney disease (CKD) has a complicated interrelationship with various comorbidities. The purpose of this study was to describe the prevalence of various comorbidities among veterans with CKD and compare it with other datasets like Kidney Early Evaluation Program (KEEP), National Health and Nutrition Examination Survey (NHANES) and Medicare. Patients who had at least one outpatient visit in year 2007 (1 January 2007 to 31 December 2007) were included in the study (n = 75,787). Glomerular filtration rate (eGFR) was estimated by the Modification of Diet in Renal Disease (MDRD) study equation. CKD prevalence was calculated based on one or two serum creatinine values at least 3 months apart. Demographic data were obtained including age, gender, race, weight, height and body mass index (BMI). The prevalence of various comorbidities was also collected based on ICD 9 codes from the problem list. The prevalence of CKD among veterans was 47.3%, much higher than estimated in the US population. Patients with CKD were more likely to have any vascular disease (36.89% vs. 14.87%), diabetes (34.18% vs. 17.83%), hypertension (86.65% vs. 57.56%), and cancer (18.69% vs. 9.23%). Irrespective of age, the prevalence of vascular disease was much higher among veterans with CKD. The prevalence of coronary artery disease, peripheral vascular disease, and cancer was much higher among elderly veterans with CKD as compared to other datasets. CKD is a growing endemic associated with a high frequency of concomitant chronic illnesses. Public health resources should be applied for early recognition and risk modification of CKD.