Effects of dietary sodium on sympathetic nervous system control of cardiovascular function.
Effects of dietary sodium on sympathetic nervous system control of cardiovascular function.
复制标题
膳食钠对交感神经系统控制心血管功能的影响。
DOI：
10.1111/j.1474-8673.1984.tb00090.x
复制
发表时间：
1984
期刊：
影响因子：
--
通讯作者：
Vollmer,RR
中科院分区：
文献类型：
--
作者：
Vollmer,RR
表征交感神经系统对心血管功能的控制的适应性的信息体响应于膳食钠摄入量的变化而发生，该信息体正在迅速扩展。神经系统内的多个部位已被证明对钠可用性的变化敏感，包括压力感受器、大脑中的心血管调节中心和外周交感神经元。此外，已知膳食钠影响能够调节交感神经元功能的激素系统的活性水平。与交感神经元相互作用研究最广泛的激素系统是肾素-血管紧张素系统。其他激素系统如肾上腺素、激肽和利钠激素也与钠稳态有关。然而，很少有人知道他们的作用，在调节交感神经活动的改变，钠的摄入量。进一步阐明膳食钠和心血管系统的交感神经控制之间的相互作用，将大大增加我们对心血管调节机制的理解。
The body of information which characterizes the adaptations in sympathetic nervous system control of cardiovascular function that occur in response to changes in dietary sodium intake is rapidly expanding. Multiple sites within the nervous system have been shown to be sensitive to variations in sodium availability, including the baroreceptors, cardiovascular regulatory centres in the brain, and the peripheral sympathetic neurones. In addition, dietary sodium is known to influence the level of activity of hormonal systems which are capable of modulating sympathetic neuronal function. The hormonal system that has been most widely investigated with respect to interactions with sympathetic neurones is the renin-angiotensin system. Other hormonal systems such as the prostaglandins, kinins, and natriuretic hormone have also been linked to sodium homeostasis. However, much less is known about their role in modulating sympathetic activity in response to alterations in sodium intake. Further elucidation of the interactions between dietary sodium and sympathetic neural control of the cardiovascular system should add significantly to our understanding of the mechanisms involved in cardiovascular regulation.