A Complete Monographic Study on Abies pindrow Royle Aerial Parts

A Complete Monographic Study on Abies pindrow Royle Aerial Parts
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冷杉平卓罗伊尔空中部件的完整专题研究

DOI:
10.4172/pharmaceutical-sciences.1000318
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发表时间:
2017
期刊:
影响因子:
--
通讯作者:
S. Kumar
S. Kumar
中科院分区:
--
文献类型:
--
作者:
D. Kumar;S. Kumar

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建立传统植物生药标准是选择经过验证的植物进行研究的前提。印度传统植物冷杉(银杉;松科)的生药标准已经制定。叶至中脉的横切面显示存在表皮、栅栏细胞、维管束、海绵细胞、韧皮部和木质部,而茎显示存在木栓、皮层、周环纤维、韧皮部、木质部和髓。在粉末显微镜下观察到有凹陷的血管、周环纤维、单细胞覆盖毛状体和无细胞气孔。总灰分分别比酸不溶性灰分和水溶性灰分多约2倍和4倍。发现醇溶性提取值略低于水溶性提取值。外来有机物、水分和单宁含量均为零,分别为 8.03% 和 2.11% w/w。溶胀指数、起泡指数、苦味值和溶血值分别为1.2、<100、4000和零。发现挥发油含量为 0.85% v/w。还生成了挥发油的定量化学参数,即酸值、皂化值、酯值、羟基值、碘值、过氧化物值、乙酰值和不皂化物。经估算,有毒残留物的含量符合世界卫生组织规定的限值。从植物化学角度来看,该植物含有脂肪、三萜类化合物、类黄酮、类固醇、单宁、蛋白质和碳水化合物。使用合适的流动相,正己烷、氯仿、甲醇提取物和挥发油的薄层色谱分别显示十一个、八个、十个和十一个斑点。
The establishment of pharmacognostic standards of traditional plants is prerequisite for selecting authenticated plants for research purpose. The pharmacognostic standards of an Indian traditional plant, i.e., Abies pindrow Royle (Silver Fir; family- Pinaceae) has been established. Transverse section of leaf through midrib showed presence of epidermis, palisade cells, vascular bundles, spongy cells, phloem and xylem whereas stem showed the presence of cork, cortex, pericyclic fibres, phloem, xylem and pith. Pitted vessel, pericyclic fibre, unicellular covering trichome and anomocytic stomata were observed in powdered microscopy. Total ash was about 2 and 4 times more than acid insoluble and water soluble ash, respectively. Alcohol soluble extractive value was found to be slightly less than water soluble extractive value. Foreign organic matter, moisture and tannin contents were found to be nil, 8.03% and 2.11% w/w, respectively. Swelling index, foaming index, bitterness value and haemolytic value were found to be 1.2, <100, 4000 and nil, respectively. Volatile oil content was found to be 0.85% v/w. Quantitative chemical parameters viz., acid-, saponification-, ester-, hydroxyl-, iodine-, peroxide-, acetyl values and unsaponifiable matter for the volatile oil were also generated. The content of toxic residues was estimated and found to comply with the limits as per World Health Organization. Phytochemically, the plant was found to contain fats, triterpenoids, flavonoids, steroids, tannins, proteins and carbohydrates. Thin layer chromatography of n-hexane, chloroform, methanol extracts and volatile oil showed eleven, eight, ten and eleven spots, respectively, using suitable mobile phases.