Cutaneous Primary NUT Carcinoma With BRD3-NUTM1 Fusion
Cutaneous Primary NUT Carcinoma With BRD3-NUTM1 Fusion
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BRD3-NUTM1 融合的皮肤原发性 NUT 癌
DOI：
10.1097/pas.0000000000001801
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发表时间：
2021
影响因子：
5.6
通讯作者：
Mori Taisuke
中科院分区：
文献类型：
--
作者：
Nishimura Yuuki;Ryo Eijitsu;Yamazaki Naoya;Yatabe Yasushi;Mori Taisuke
致编辑：我们饶有兴趣地阅读了 Macagno 等人最近发表的关于孔瘤和孔癌 NUT 免疫组织化学分析的文章。他们的大型研究结果与我们第一份关于毛孔瘤和毛孔癌中 YAP1-NUTM1 重排的报告一致。 2 Macagno 及其同事使用 835 例各种皮肤表皮或附件上皮肿瘤病例证明，NUT 在具有小汗腺孔瘤和汗孔癌的不同形态学亚组中更常见。尽管我们完全同意 NUT 免疫组织化学染色是准确的并且可以用作孔状肿瘤的特异性诊断标志物，但在此，我们报告了
To the Editor: We read with great interest the recent article published by Macagno et al1 on NUT immunohistochemical analysis of poromas and porocarcinomas. The results of their large study were consistent with those of our first report on YAP1-NUTM1 rearrangement in both poromas and porocarcinomas. 2 Using 835 cases with various cutaneous epidermal or adnexal epithelial neoplasms, Macagno and colleagues proved that NUT occurred more frequently in a distinct morphologic subgroup with eccrine poromas and porocarcinomas. Although we completely agree that NUT immunohistochemical staining is accurate and can be used as a specific diagnostic marker for poroid neoplasms, herein, we report an